BIOLOGY CONNECT ACCESS CARD 1-SEMESTER
12th Edition
ISBN: 9781264019090
Author: Raven
Publisher: MCG/CREATE
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Textbook Question
Chapter 42, Problem 7A
G protein–coupled receptors are involved in the nervous system by
a. controlling the release of neurotransmitters.
b. controlling the opening and closing of Na+ channels during an action potential.
c. controlling the opening and closing of K+ channels during an action potential.
d. acting as receptors for neurotransmitters on postsynaptic cells.
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A hormone signals through a G protein- coupled receptor as shown in the diagram. After the production of IP3, which of these events will MOST quickly stop the transduction of the signal?
A. the hydrolysis of IP3
B. the hydrolysis of GTP
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D. the hydrolysis of the hormone
Paracrine signaling is characterized by ligands that are
a. produced by the cell itself.
b. secreted by neighboring cells.
c. present on the plasma membrane of neighboring cells.
d. secreted by distant cells.
Dopamine, epinephrine (or norepinephrine) and histamine are important neurotransmitter agonists. When these ligands interact with their cellular receptors, how do they mainly elicit their responses? Choose the correct answer(s) and explain why.
a) Activate adenylyl cyclase directly, leading to increased intracellular cAMP levels
b) Activate phospholipase C
c)Induce or inhibit synthesis of ligand specific intracellular proteins
d) Open or close ligand gated ion channels
e) Regulate intracellular second messengers through G-protein-coupled receptors
Chapter 42 Solutions
BIOLOGY CONNECT ACCESS CARD 1-SEMESTER
Ch. 42.1 - Differentiate between subdivisions of the...Ch. 42.1 - Prob. 2LOCh. 42.1 - Explain the roles of the different nervous system...Ch. 42.2 - Contrast the relative concentrations of important...Ch. 42.2 - Prob. 2LOCh. 42.2 - Prob. 3LOCh. 42.3 - Prob. 1LOCh. 42.3 - Prob. 2LOCh. 42.3 - Prob. 3LOCh. 42.4 - Prob. 1LO
Ch. 42.4 - Prob. 2LOCh. 42.4 - Prob. 3LOCh. 42.5 - Describe the organization of the peripheral...Ch. 42.5 - Prob. 2LOCh. 42.5 - Prob. 3LOCh. 42.5 - Prob. 4LOCh. 42 - Data analysis Draw the resulting potentials for...Ch. 42 - Prob. 2DACh. 42 - Which of the following best describes the...Ch. 42 - The ____ cannot be controlled by conscious...Ch. 42 - Prob. 3UCh. 42 - Inhibitory neurotransmitters a. hyperpolarize...Ch. 42 - White matter is ______, and gray matter is...Ch. 42 - During an action potential a. the rising phase is...Ch. 42 - Prob. 7UCh. 42 - Imagine that you are doing an experiment on the...Ch. 42 - The Na+/K+ ATPase pump is a. not required for...Ch. 42 - Prob. 3ACh. 42 - The following is a list of the components of a...Ch. 42 - Prob. 5ACh. 42 - As you sit quietly reading this sentence, the part...Ch. 42 - G proteincoupled receptors are involved in the...Ch. 42 - Tetraethylammonium (TEA) is a drug that blocks...Ch. 42 - Describe the status of the Na+ and K+ channels at...Ch. 42 - Describe the steps required to produce an...Ch. 42 - Prob. 4S
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- When activated extracellularly, G protein-coupled receptors (GPCRs) initiate which of the following? (select all that apply) a G protein signaling mechanism inside the cell. b) A G protein signaling mechanism outside the cell. c) Transporters to uptake degraded neurotransmitters for recycling. d) The release of neurotransmitter molecules into the postsynaptic cell.arrow_forwardThe receptors for lipid-soluble signaling molecule, such as steroid hormones, are located: A) in the nucleus of the target cell B) in the cytoplasm of the target cell C) in the bloodstream D) inserted into the membrane of the target cell E) Lipid-insoluble hormones do not need receptorsarrow_forwardIn intercellular signaling pathways, some receptor proteins can also act as a transcription factor (changing gene expression), because these receptors are ________. A) Group of answer choices B) Intracellular receptors C) Membrane bound receptors D) G protein coupled receptors E) Enzyme linked receptors F) Fast ligand-gated ion channelsarrow_forward
- Amplification of a chemical signal occurs when? a. phosphorylation of proteins by protein kinase receptors is balanced by the immediate removal of phosphate groups by phosphatases b. a receptor in the plasma membrane activates several “first messenger” molecules while a signal molecule is bound to it c. a cAMP molecule activates one protein kinase molecule before being converted to AMP d. a receptor activates a single first messenger and a single second messengerarrow_forwardWhen a chemical signal binds to an intracellular receptor ... a) ... it leads to the activation of G proteins. b) ... causes the receptor-hormone complex to open or close ion channels. c) ... the cell reacts faster than when a chemical signal binds to membrane-bound receptors. d) ... it leads to the formation of mRNA. e) ... the chemical signal is usually a large, water-soluble molecule.arrow_forwardAn extracellular signaling molecule binds to cell surface receptor. This cell surface receptor changes shape and activates a trimeric G-protein. What kind of receptor is this? a) Ion-channel coupled receptor b) Receptor Tyrosine Kinase c) G-Protein coupled receptor d) All of the other answers are correct e) Enzyme-coupled receptorarrow_forward
- 1) Voltage-gated ion channels on the cell body: a) allow Ca2+ to enter, leading to neurotransmitter release. b)have binding sites for neurotransmitters. c)open following entry of Na+ through ligand-gated channels. d) are inactivated by enzymes in the synaptic cleft.arrow_forwardA new antagonist molecule has been discovered that binds to and blocks plasma membrane receptors. What effect will this antagonist have on testosterone, a steroid hormone? a. It will block testosterone from binding to its receptor. b. It will block testosterone from activating cAMP signaling. c. It will increase testosterone-mediated signaling. d. It will not affect testosterone-mediated signaling.arrow_forwardIn relation to Cushing’s Syndrome, a method that some scientists have used to treat the disease is to use small molecules that bind to, but do not activate, MC2R. This type of molecule is considered an antagonist. How can an antagonist bind to the same receptor as ACTH but not activate it ? a. The antagonist binds covalently while ACTH binds non covalently b. The antagonist is only partially complimentary to the binding pocket of MC2R c. The antagonist binds to ACTH and blocks it from binding to the receptor properly d. The antagonist is the exact same structure as ACTH but since it is synthetic it doesn’t workarrow_forward
- G proteins (a) relay a message from an activated receptor to an enzyme that activates a second messenger (b) are GTP molecules (c) terminate cell signaling (d) directly activate protein kinases (e) function as first messengersarrow_forwardwhat happens when an antagonist binds to an inhibitory neurotransmitter receptor? a) it would decrease inhibitory response b) increase inhibitory response c) ion channels will open d) EPSP will occurarrow_forwardExplain whether the specificity of interaction will be high or low for each given situation. a. The concentration of the ligand's complex to the target receptor equates to the concentration of the ligand's complex to off-targets. b. The target receptor's total concentration is very much higher than the off-target's total concentration.arrow_forward
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