Concept explainers
To discuss:
The regulation of cell cycle by cyclins and cyclin-dependent kinases (Cdks).
Introduction:
Cell cycle is an essential process by which cells increase in number while maintaining its genetic stability. In an organism, it is vital for growth and regeneration. However, it has to be tightly regulated to avoid dire consequences. Unregulated repetitive cell division may lead to cancers that may prove detrimental to the organism. On the other hand, infrequent divisions may end in inadequate growth and regeneration. So the regulation of cell cycle is paramount for the organism’s survival. Cyclins, Cdks, and cell cycle checkpoints are responsible for the regulation of cell cycle.
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Chapter 4 Solutions
ANAT.+PHYS.LAB MANUAL-W/ACCESS >CUSTOM<
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- What includes motors that functionin interphase and mitotic cells, transporting organelles and sliding antiparallel microtubules past each other. The super-family includes one class, kinesin-13, that is not motile, but instead destabilizes microtubule endsarrow_forwardA thorough review of cell cycle progression and regulationarrow_forwardRegulation of the cell cycle is very important. Explain what may happen if the mechanisms regulating the cell cycle stop working.arrow_forward
- How the two daughters of a Stem Cell make the decision to self-renew or to differentiate.arrow_forwardThe Cell Cycle: During what stage of the cell cycle is the nuclear material doubled? Are the stages of mitosis occurring simultaneously on a meristem? In what material is the coded information of the cell stored?arrow_forwardWhat cellular mechanism(s) ensure that passage through the cell cycle is unidirectional and irreversible? What molecular machinery underlies these mechanism(s)?arrow_forward
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