Biology: Dynamic Science - With MindTap
Biology: Dynamic Science - With MindTap
4th Edition
ISBN: 9781305934146
Author: Russell
Publisher: Cengage
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Chapter 45, Problem 11TYK
Summary Introduction

To review:

HIV attacks helper T cells and macrophages, and wreaks havoc on the immune system. The altered impact when the virus attacks only the macrophages.

Introduction:

HIV (human immune deficiency virus) is a pathogen of humans. This virus as suggested by name; this virus causes the immune system deficient by attacking the immune cells (helper T cells and macrophages). The person infected with HIV becomes susceptible to other diseases as the immunity of that person is reduced.

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Identify the statement that does not provide accurate evidence as to why HIV is so lethal.   a. During the course of infection, HIV increases immune activation by altering intestinal physiology to let more microbes into the blood supply.   b. Immune evasion increases in many infections due to HIV virions evolving new and unrecognizable epitopes (antigens).   c. In many individuals the virus population evolves to use different receptors to gain access to a greater diversity of host immune cells.   d. HIV causes enhanced replication and proliferation of T cells, which allows the immune system to work better at defending against pathogens.
This is a hypothetical scenario. A recently emerged virus has been transmitting and mutating rapidly in humans throughout the world. If a vaccine that stops transmission of all current circulating variants of the virus in humans is utilized and herd immunity is achieved throughout the world, would this essentially stop 1) further transmission of the virus; 2) further mutation of the virus, respectively? Why/why not? Please answer the question succinctly and in bullet points!
Considering that each virus must bind to a specific cell surface receptor for attachment, explain how you would create a drug that prevents viral attachment.
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