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Biology: The Dynamic Science (Mind...

4th Edition
Peter J. Russell + 2 others
ISBN: 9781305389892

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BuyFindarrow_forward

Biology: The Dynamic Science (Mind...

4th Edition
Peter J. Russell + 2 others
ISBN: 9781305389892
Textbook Problem

Discuss Concepts Cats, dogs, and humans may develop myasthenia gravis, an autoimmune disease in which antibodies develop against acetylcholine receptors in the synapses between neurons and skeletal muscle fibers. Based on what you know of the biochemistry of muscle contraction (see Section 43.1), explain why people with this disease typically experience severe fatigue with even small levels of exertion, drooping of facial muscles, and trouble keeping their eyelids open.

Summary Introduction

To review:

Myasthenia gravis, an autoimmune disease, may develop into cats, dogs, and humans. Individuals suffering with the disease experience severe fatigue with even small levels of exertion, drooping of facial muscles, and trouble keeping their eyelids open.

Introduction:

Myasthenia gravis is a neuromuscular type of autoimmune disease. Autoimmune disease is a medical condition in which antibodies are formed against self-molecules in the cell, mostly against the receptors. The antibodies are formed against acetylcholine receptors in the synapse of neurons and muscle cells.

Explanation

Neurotransmitters are signaling molecules, which are released from neurons or brain cells and after releasing, it binds to its receptors present on muscle cells; that means neurotransmitters are responsible for the communication between neurons and muscles.

The signal from the brain travels through the neurons and releases in the form of neurotransmitter from the nerve endings in the synapse of neurons and muscles. The acetylcholine neurotransmitter gets released from the nerve endings into the synapse and binds to its receptors on the muscle cell and causes muscle contraction...

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