CAMPBELL BIOLOGY IN FOCUS (LL)-W/MOD.MA
CAMPBELL BIOLOGY IN FOCUS (LL)-W/MOD.MA
3rd Edition
ISBN: 9780135686065
Author: Urry
Publisher: PEARSON
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Chapter 4.7, Problem 3CC

MAKE CONNECTIONS The polypeptide chain that makes up a tight junction weaves back and forth through the membrane four times, with two extracellular loops, and one loop plus short C-terminal and N-terminal tails in the cytoplasm. Looking at Figure 3.18, whatWhat would you predict about the amino acids making up the tight junction protein?

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Match each description with the type of transmembrane protein
Drawn below is a schematic of a transmembrane protein. Extracellular Cell membrane Cytosolic side (a) From the list below, select the amino acid(s) that might by more common in the extracellular domain of this membrane protein and whose side- chain can form hydrogen bonds with the surrounding water molecules. Explain why you selected this option(s). Lysine Serine Phenylalanine Methionine (b) From the list below, select the amino acid(s) that would likely be found in the transmembrane/ membrane spanning domain of this protein and whose side- chain interacts with the lipid bilayer. Lysine Serine Phenylalanine Methionine
Explain how the amphipathic (containing both hydrophobic and hydrophilic sides) protein (shown; left)would be anchored in the phospholipid bilayer (shown; right); which portion do you predict would besticking out towards the water? Which portion would be hiding inside the membrane?
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