Biology
Biology
5th Edition
ISBN: 9781260487947
Author: BROOKER
Publisher: MCG
bartleby

Concept explainers

bartleby

Videos

Textbook Question
Book Icon
Chapter 5.1, Problem 1CS

Core Skill: Modeling The goal of this modeling challenge is to propose a model for a transmembrane protein.

Modeling Challenge: As shown in Figure 5.2, some α helices, which are called transmembrane a helices, may be inserted into the hydrophobic region of a membrane and span the entire membrane. Let’s suppose a protein in the plasma membrane has 5 transmembrane α helices. The loops that connect these 5 transmembrane segments are relatively short, except for the one that connects transmembrane segments 4 and 5, which is longer. The amino end projects into the cytosol. Draw a model of this transmembrane protein in the plasma membrane. In your model, draw the transmembrane a helices as cylinders and label them 1 through 5. Also label the amino and carboxyl ends and the cytosol and extracellular environment.

Blurred answer
Students have asked these similar questions
Multipass transmembrane proteins synthesized by ribosomes on the rough endoplasmic reticulum generally have which of the following arrangements of start-transfer  and stop-transfer  signals? multiple start signals and multiple stop signals (to allow multiple transmembrane regions) multiple start signals, but only one stop signal (to allow only one transmembrane region) only one start signal, but multiple stop signals (to allow only one transmembrane region) only one start signal, and only one stop signal (to allow only one transmembrane region) only one stop signal, and only one start signal (to allow only one transmembrane region)
WHAT IF? Some membrane proteins diffuse faster in the plasma membrane when the cytoskeleton or the extracellular matrix is artificially removed than when cells are unperturbed. Explain why.
Paper link   -     https://www.jneurosci.org/content/40/8/1756.long Neuronal Mitochondria Modulation of LPS-Induced Neuroinflammation     What is LPS (not just what does it stand for)? Why is it used as a model for neuroinflammation? Describe microglia: where are they found, what role do they play, why can't that role be carried out the same way it is in the rest of the body? Mitofusin2 (Mfn2) is a mitochondrial protein. What is its apparent role? Can you think of a reason why overexpression could be protective against a stress? Is it reasonable that overexpression of this gene could also cause problems (if so, how)? How did the authors arrange that Mfn2 was only upregulated in the brain and spinal cord of TMFN mice, and not in other tissues of the mice? How do they demonstrate this? Briefly describe the roles of these molecules in immunity/inflammation:IL-1βIL-6IL-10TNFα They all belong to a class of molecules; what is that class called? What evidence do the authors provide that…
Knowledge Booster
Background pattern image
Biology
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
SEE MORE QUESTIONS
Recommended textbooks for you
Text book image
Biochemistry
Biochemistry
ISBN:9781305961135
Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:Cengage Learning
Text book image
Biomedical Instrumentation Systems
Chemistry
ISBN:9781133478294
Author:Chatterjee
Publisher:Cengage
Text book image
Biology (MindTap Course List)
Biology
ISBN:9781337392938
Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher:Cengage Learning
The Cell Membrane; Author: The Organic Chemistry Tutor;https://www.youtube.com/watch?v=AsffT7XIXbA;License: Standard youtube license