Concept explainers
Core Skill: Modeling The goal of this modeling challenge is to propose a model for a transmembrane protein.
Modeling Challenge: As shown in Figure 5.2, some α helices, which are called transmembrane a helices, may be inserted into the hydrophobic region of a membrane and span the entire membrane. Let’s suppose a protein in the plasma membrane has 5 transmembrane α helices. The loops that connect these 5 transmembrane segments are relatively short, except for the one that connects transmembrane segments 4 and 5, which is longer. The amino end projects into the cytosol. Draw a model of this transmembrane protein in the plasma membrane. In your model, draw the transmembrane a helices as cylinders and label them 1 through 5. Also label the amino and carboxyl ends and the cytosol and extracellular environment.
Want to see the full answer?
Check out a sample textbook solutionChapter 5 Solutions
Biology
- VISUAL SKILLS Carbohydrates are attached to plasmamembrane proteins in the ER (see Figure 7.9). On whichside of the vesicle membrane are the carbohydrates during transport to the cell surface?arrow_forwardCan someone please explain in technical detail how all the proteins in the Outer Membrane Proteins (OMP) system work? Thank youarrow_forwardpls help ASAP, thank you! “which feature of protein folding is NOT accurate?”arrow_forward
- performing corrections: Which coat protein is involved in transport of vesicles from the trans-Golgi network to the plasma membrane, endosomes, and lysosomes A. Clathrin B.COPI C.COPII D.Trench coat I had originally selected option C but got it wrong, what is the correct answer with explanation and how is the answer i selected incorrect?arrow_forwardThanks in advance!!!1) What are the basic components of a cell’s membrane and how is it organized? What are the functions? Why is it called a “fluid mosaic” membrane?2) Distinguish Ionic, Covalent, Hydrogen Bonding, and Van der Waals (Hydrophobic).4) Distinguish DNA from RNA, what is the same, what is different? Importance in function?. What is the difference between a nucleotide and a nucleoside. 5) Why can cell membranes be polar? What does polar mean?6) What are the basic cytoskeletal components of a cell? What does an animal cell have that no other cell has in the cytoskeleton? 7) How does an enzyme help a reaction proceed? How does heat, chemicals, and pH affect enzyme activity? 8) From a cellular standpoint, what is the difference between kinetic and potential energy? What is the major molecule that cells use for energy? What are high energy molecules found in the cell and how are used to make ATP?9) What are NAD+, NADH, FAD+, FADH2. How’s it regulated? 10) What are the four…arrow_forward. MAKE CONNECTIONS How are the Casparian strip andtight junctions similar (see Figure 6.30)?arrow_forward
- WHAT IF? Imagine a protein that functions in the ERbut requires modification in the Golgi apparatus beforeit can achieve that function. Describe the protein’s paththrough the cell, starting with the mRNA molecule thatspecifies the protein.arrow_forwardQ1: In what ways is the plasma membrane a barrier, and in what ways is it a gatekeeper? Q2: Why can’t ions (such as Na+) cross the plasma membrane without the help of a transport protein? Q3: If no energy were available to the cell, what forms of transport would not be able to occur? What forms of transport could occur?arrow_forwardQuestion:- Given the very complex lipid composition of cell membranes, what variations exist within the different membranes of organelles in an animal cell? What are the functional consequences of these differences?arrow_forward
- Q. In protein structure modelling, how you identify the best model? Name and explain the parameters you take into consideration while selecting a model. ( Subject: Bioinformatics)arrow_forwardQ6: A protein that spans the phospholipid bilayer one or more times isO a glycoprotein.O a transmembrane protein.O an extracellular matrix protein.O a peripheral protein.arrow_forwardHow can we improve crystallizationand single-particle cryoelectronmicroscopy techniques to obtain high-resolution structures of all importantmembrane channels and transporters?What new concepts might thesestructures reveal?arrow_forward
- BiochemistryBiochemistryISBN:9781305961135Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougalPublisher:Cengage LearningBiology (MindTap Course List)BiologyISBN:9781337392938Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. BergPublisher:Cengage Learning