Essential Cell Biology
Essential Cell Biology
4th Edition
ISBN: 9780815344544
Author: Keith Roberts, Karen Hopkin, Alexander D Johnson, Martin Raff, Dennis Bray, Bruce Alberts, Julian Lewis, Peter Walter
Publisher: TAYLOR
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Chapter 6, Problem 15Q

A.

Summary Introduction

To explain: The consequences that would arise if a eukaryotic chromosome contained only one origin of replication at

  1. (i) the exact center of the chromosome
  2. (ii) at one end of the chromosome

Introduction: Both eukaryotes and prokaryotes have their DNA packed in chromosomes. Eukaryotic chromosomes are tightly packed and are linear. Replication begins at certain locations on DNA known as origins of replication. Eukaryotes have end-replication problem, as their ends have telomeres and thus the DNA at the ends of chromosomes are not fully copied at each round of replication. The single-stranded overhangs produced form protective loops.

B.

Summary Introduction

To explain: The consequences that would arise if a eukaryotic chromosome lacked one or both telomeres.

Introduction: Both eukaryotes and prokaryotes have their DNA packed in chromosomes. Eukaryotic chromosomes are tightly packed and are linear. Replication begins at certain locations on DNA known as origins of replication. Eukaryotes have end-replication problem, as their ends have telomeres and thus the DNA at the ends of chromosomes are not fully copied at each round of replication. The single-stranded overhangs produced form protective loops.

C.

Summary Introduction

To explain: The consequences that would arise if a eukaryotic chromosome had no centromere.

Introduction: Both eukaryotes and prokaryotes have their DNA packed in chromosomes. Eukaryotic chromosomes are tightly packed and are linear. Replication begins at certain locations on DNA known as origins of replication. Eukaryotes have end-replication problem, as their ends have telomeres and thus the DNA at the ends of chromosomes are not fully copied at each round of replication. The single-stranded overhangs produced form protective loops.

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