Concept explainers
A.
To explain: The consequences that would arise if a eukaryotic chromosome contained only one origin of replication at
- (i) the exact center of the chromosome
- (ii) at one end of the chromosome
Introduction: Both eukaryotes and prokaryotes have their DNA packed in chromosomes. Eukaryotic chromosomes are tightly packed and are linear. Replication begins at certain locations on DNA known as origins of replication. Eukaryotes have end-replication problem, as their ends have telomeres and thus the DNA at the ends of chromosomes are not fully copied at each round of replication. The single-stranded overhangs produced form protective loops.
B.
To explain: The consequences that would arise if a eukaryotic chromosome lacked one or both telomeres.
Introduction: Both eukaryotes and prokaryotes have their DNA packed in chromosomes. Eukaryotic chromosomes are tightly packed and are linear. Replication begins at certain locations on DNA known as origins of replication. Eukaryotes have end-replication problem, as their ends have telomeres and thus the DNA at the ends of chromosomes are not fully copied at each round of replication. The single-stranded overhangs produced form protective loops.
C.
To explain: The consequences that would arise if a eukaryotic chromosome had no centromere.
Introduction: Both eukaryotes and prokaryotes have their DNA packed in chromosomes. Eukaryotic chromosomes are tightly packed and are linear. Replication begins at certain locations on DNA known as origins of replication. Eukaryotes have end-replication problem, as their ends have telomeres and thus the DNA at the ends of chromosomes are not fully copied at each round of replication. The single-stranded overhangs produced form protective loops.
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