Essential Cell Biology
Essential Cell Biology
4th Edition
ISBN: 9780815344544
Author: Keith Roberts, Karen Hopkin, Alexander D Johnson, Martin Raff, Dennis Bray, Bruce Alberts, Julian Lewis, Peter Walter
Publisher: TAYLOR
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Chapter 6, Problem 16Q
Summary Introduction

To draw: A sketch showing the result if a DNA polymerase that runs in 3ʹ-5ʹ direction were to remove an incorrect nucleotide from a growing DNA strand.

Introduction:

DNA is the blueprint of life and contains genetic information. Replication of DNA is semi-conservative. During DNA replication, DNA polymerase enzyme molecules catalyze the synthesis of DNA. They add DNA nucleotides to an existing strand in 5ʹ-3ʹ direction with high fidelity. It proofreads the DNA strand to check for any errors or mismatch with an error rate of 107 polymerized nucleotides.

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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY