EBK MATLAB: AN INTRODUCTION WITH APPLIC
5th Edition
ISBN: 8220102007642
Author: GILAT
Publisher: YUZU
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Chapter 6, Problem 29P
The concentration of a drug in the body CPcan be modeled by the equation:
where DG is the dosage administered (mg), Vdis the volume of distribution (L), kdis the absorption rate constant (h-1) k is the elimination rate constant (h-1), and t is the time (h) since the drug was administered. For a certain drug, the following quantities are given: DG= 150mg, Vd, = 50L, ka= 1.6 h-1, and ke= 0.4 h-1.
(a) A single dose is administered at t = 0. Calculate and plot CPversus t for 10h.
(b) A first dose is administered at t = 0, and subsequently four more doses are administered at intervals of 4 h (i.e., at t = 4, 8, 12, 16). Calculate and plot CP, versus t for 24 h.
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Chapter 6 Solutions
EBK MATLAB: AN INTRODUCTION WITH APPLIC
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