BIOLOGY >PRINT UPGRADE<
11th Edition
ISBN: 9780357091586
Author: Solomon
Publisher: CENGAGE L
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Chapter 6, Problem 8TYU
Scaffold proteins (a) release kinases and phosphatases into the extracellular fluid (b) bind G proteins to cell membranes (c) increase accuracy but slow signaling cascades (d) organize groups of intracellular signaling molecules into signaling complexes (e) are transcription factors found mainly in plant cells
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Chapter 6 Solutions
BIOLOGY >PRINT UPGRADE<
Ch. 6.1 - Describe the four main processes essential for...Ch. 6.1 - What is the sequence of events that takes place in...Ch. 6.1 - Prob. 2CCh. 6.2 - Compare three types of signaling molecules:...Ch. 6.2 - Prob. 1CCh. 6.2 - Prob. 2CCh. 6.2 - Prob. 3CCh. 6.3 - Identify mechanisms that make reception a highly...Ch. 6.3 - Prob. 4LOCh. 6.3 - Prob. 1C
Ch. 6.3 - Prob. 2CCh. 6.3 - Prob. 3CCh. 6.3 - Prob. 4CCh. 6.4 - Prob. 5LOCh. 6.4 - Trace the sequence of events in signal...Ch. 6.4 - How is an extracellular signal converted to an...Ch. 6.4 - Prob. 2CCh. 6.4 - Prob. 3CCh. 6.5 - Prob. 7LOCh. 6.5 - Prob. 8LOCh. 6.5 - Prob. 1CCh. 6.5 - Prob. 2CCh. 6.5 - Prob. 3CCh. 6.6 - Cite evidence supporting a long evolutionary...Ch. 6.6 - Prob. 1CCh. 6 - During signal transduction (a) the cell converts...Ch. 6 - When a signaling molecule binds with a receptor,...Ch. 6 - G proteinlinked receptors (a) inactivate G...Ch. 6 - Prob. 4TYUCh. 6 - Prob. 5TYUCh. 6 - Calcium ions (a) can act as second messengers (b)...Ch. 6 - When growth hormone binds to an enzyme-linked...Ch. 6 - Scaffold proteins (a) release kinases and...Ch. 6 - Prob. 9TYUCh. 6 - Prob. 10TYUCh. 6 - More than 500 genes have been identified in the...Ch. 6 - Prob. 12TYUCh. 6 - Prob. 13TYUCh. 6 - EVOLUTION LINK Cell signaling in plant and animal...Ch. 6 - EVOLUTION LINK Some of the same G proteinlinked...Ch. 6 - Prob. 16TYU
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- During signal transduction (a) the cell converts an extracellular signal into an intracellular signal that leads to a change in some cell process (b) a signaling molecule directly activates or represses several genes (c) each enzymecatalyzes production of one molecule of product (d) enzymes in the signal cascade remain active until the last component of the pathway alters a cellular process (e) the signal is terminated by cyclic AMParrow_forwardG protein–linked receptors (a) inactivate G proteins (b) activate first messengers (c) consist of 18 transmembrane alpha helices (d) have a tail that extends into the cytosol with a binding site for a G protein (e) are located in the cytoplasm or nucleusarrow_forwardWhen a signaling molecule binds with a receptor, (a) G proteins are inactivated (b) a third messenger is activated (c) cell signaling is terminated (d) cAMP is produced by the receptor (e) the receptor becomes activatedarrow_forward
- a) Create a diagram which illustrates the typical signalling mechanism of action of kinase- linked receptors and possible routes of communication (autocrine etc.). Should show the specific molecules involved, the mechanisms of signal transduction and indicate the different pathways that are activated. It should include a specific example of a receptor, ligand and signalling pathway for each general class. Include as wide a variety of ligands and modes of action as you can. for a novel pathway. Superfamily Give the superfamily to which the receptor belongs Accession Give the Uniprot accession number Name Give the molecule name Species Give the species Ligand What is the ligand, or class of ligands which bind to this receptor? What are the physiological processes involved? Is this autocrine, paracrine or endocrine or some combination of them? What is the pathology of the receptor? Key physiological process involved Mechanism of What are the downstream actions of the receptor? Which…arrow_forward(i) For non-lipid soluble signalling molecules, which class of receptors are required? Please give two examples of non-lipid signalling molecules and explain how these signalling molecules induce intracellular signalling to change the cell behaviour. (ii) Compare and contrast beta catenin and p53 signalling, and explain their functions in the nucleus.arrow_forwardThe transforming growth factory beta (TGF-b) family of hormones / growth factors are dimers and they interact with specific receptors. Which of the following statements about these receptors is correct? a) A receptor complex is formed from a type 1 and a type 2 receptor b) A receptor complex is formed between the ligand and the receptor c) This family interacts with a single serine- threonine kinase receptor d) The major receptor is intracellular e) The receptor is a G-protein receptorarrow_forward
- Binding of a signaling molecule to which typeof receptor leads directly to a change in thedistribution of substances on opposite sides of themembrane?(A) intracellular receptor(B) G protein-coupled receptor(C) phosphorylated receptor tyrosine kinase dimer(D) ligand-gated ion channelarrow_forwardIdentify which of the following statements is a lie? Select one: a. The docking of ligands to the receptor causes receptor-associated proteins to activate another protein to continue the signaling cascade and one example of this event is the binding of epidermal growth factor (EGF) to the EGF receptor . b. Ligands are important to initiate signal Transduction pathway. c. Ligands detach from the cell surface receptor in order to change the conformation of the receptor and initiate the signaling pathway.arrow_forwardAn extracellular signaling molecule binds to cell surface receptor. This cell surface receptor changes shape and activates a trimeric G-protein. What kind of receptor is this? a) Ion-channel coupled receptor b) Receptor Tyrosine Kinase c) G-Protein coupled receptor d) All of the other answers are correct e) Enzyme-coupled receptorarrow_forward
- 47. Order the sequence of Canonical signaling via Frizzled receptors. i) β-catenin can now promote proliferation and stem cell state ii) Frizzled receptor signals for dishevelled and axin binding to itself iii) LRP assisted with Wnt binding to frizzled receptor iv) Preventing the activation of GSK-β which signals for phosphorylation A. iii ->ii-> iv-> i B. iv-> iii -> ii-> i C. i-> ii-> iv-> iii D. iii-> iv-> ii-> iarrow_forwardProtein phosphorylation is commonly involved with all of thefollowing except(A) activation of receptor tyrosine kinases.(B) activation of protein kinase molecules.(C) activation of G protein-coupled receptors.(D) regulation of transcription by signaling molecules.arrow_forwardSignaling by tyrosine kinase receptors is generally associated with all of the following except: OA) receptor dimerization B) growth factor responses C) heterotrimeric G proteins OD) cross phosphorylation E) generating protein binding sites due to phosphorylationarrow_forward
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