Bio 121 Campbell Biology Truman College
Bio 121 Campbell Biology Truman College
17th Edition
ISBN: 9781323670637
Author: Urry, Cain
Publisher: PEARSON
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Chapter 6, Problem 8TYU

SCIENTIFIC INQUIRY Imagine protein X, destined to span the plasma membrane. Assume that the mRNA carrying the genetic message for protein X has already been translated by ribosomes in a cell culture. If you fractionate the cells (see Figure 6.4), in which fraction would you find protein X? Explain by describing its transit through the cell.

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If you did a classic Pulse-Chase experiment to follow the path of a secreted protein, and you forgot to do the Chase, which of the following would you observe?     No radioactivity would be seen in any of the structures.     Radioactivity would increase first in rough ER, then Golgi Complex, then secretory vesicles, but it would remain high in all, never decreasing.     Nothing would change     Radioactivity would increase in all 3 structures simultaneously and stay high.
Describe, in detail, the steps involved in the synthesis of an integral membrane protein located in the plasma membrane. Begin with the ribosome, end with the plasma membrane.
Free ribosomes in the cytosol and ribosomes bound to the ER membrane have: 1) different types of small subunits but the same large subunits  2) the same types of large and small subunits  3) different types of large and small subunits 4) different types of large subunits the same small subunits

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Bio 121 Campbell Biology Truman College

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