Chapter 7, Problem 1MTE

(a)

Summary Introduction

To explain: The reason why hemoglobin variants do not generate same symptoms.

Concept introduction: Hemoglobin is the major oxygen carrying protein in the body. It carries oxygen from the lungs and delivers it to tissues for cellular metabolism. It has four polypeptide chains that make up the four sub units of the hemoglobin. Hemoglobin variants have altered oxygen-binding capacity.

Summary Introduction

To explain: The way in which the symptoms of thalassemia differ.

Concept introduction: Hemoglobin is the major oxygen carrying protein in the body. It carries oxygen from the lungs and delivers it to tissues for cellular metabolism. It has four polypeptide chains that make up the four sub units of the hemoglobin. Hemoglobin variants have altered oxygen-binding capacity. Thalassemia is a result of a type of hemoglobian variant.

Summary Introduction

To explain: The hemoglobin variants that appear to offer a selective advantage under certain conditions.

Concept introduction: Hemoglobin is the major oxygen carrying protein in the body. It carries oxygen from the lungs and delivers it to tissues for cellular metabolism. It has four polypeptide chains that make up the four sub units of the hemoglobin. Hemoglobin variants have altered oxygen-binding capacity.

(b)

Summary Introduction

To describe: The structure and function of motor proteins.

Concept introduction: Motor proteins are the bridges between the two microtubules. Microtubules are involved in segregation of the sister chromatids during anaphase of the mitosis.

Summary Introduction

To explain: The fibrous proteins against which the motor proteins exert force.

Concept introduction: Motor proteins are the bridges between the two microtubules. Microtubules are involved in segregation of the sister chromatids during anaphase of the mitosis.

Summary Introduction

To explain: The way in which motor proteins differ from actin-myosin system.

Concept introduction: Motor proteins are the bridges between the two microtubules. Myosin proteins are those which bind on to actin microfilaments of the cell cytoskeleton.

(c)

Summary Introduction

To explain: The way in which immunological memory is exploited in the development of vaccines for viral and bacterial infections.

Concept introduction: Vaccines contain the antigen which can be a toxin or surface protein of a pathogen or any other molecule that is part of the pathogen in order to give active acquired immunity against pathogen infection or toxin released by the organism.

Summary Introduction

To explain: The factors that make a vaccine most effective for preventing disease.

Concept introduction: Vaccines contain the antigen which can be a toxin or surface protein of a pathogen or any other molecule that is part of the pathogen in order to give active acquired immunity against pathogen infection or toxin released by the organism.