Concepts of Genetics (12th Edition)
Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 7, Problem 1PDQ

HOW DO WE KNOW? In this chapter, we have focused on sex differentiation, sex chromosomes, and genetic mechanisms involved in sex determination. At the same time, we found many opportunities to consider the methods and reasoning by which much of this information was acquired. From the explanations given in the chapter, you should answer the following fundamental questions?

  1. (a) How do we know whether or not a heteromorphic chromosome such as the Y chromosome plays a crucial role in the determination of sex?
  2. (b) How do we know that in humans the X chromosomes play no role in human sex determination, while the Y chromosome causes maleness and its absence causes femaleness?
  3. (c) How do we know that Drosophila utilizes a different sex-determination mechanism than mammals, even though it has the same sex-chromosome compositions in males and females?
  4. (d) How do we know that X chromosomal inactivation of either the paternal or maternal homolog is a random event during early development in mammalian females?
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How do we know whether or not a heteromorphic chromosome such as the Y chromosome plays a crucial role in the determination of sex?
The Amami spiny rat (Tokudaia osimensis) lacks a Y chromosome, yet scientists at Hokkaido University in Japan have reported that key sex-determining genes continue to be expressed in this species. Provide possible explanations for why male differentiation can still occur in this mammalian species despite the absence of a Y chromosome.
Butterflies have an X-Y sex-determination system that is different from that of flies or humans. Female butterflies may be either XY or X0, while butterflies with two or more X chromosomes are males. This photograph shows a tiger swallowtail gynandromorph, which is half male (left side) and half female (right side). Given that the first division of the zygote divides the embryo into the future right and left halves of the butterfly, propose a hypothesis that explains how nondisjunction during the first mitosis might have produced this unusual-looking butterfly.   Question is also in the picture.

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Concepts of Genetics (12th Edition)

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