Concept explainers
The proportion of deaths due to lung cancer in males ages 15-64 in England and Wales during the period 1970-1972 was 12%. Suppose that of 20 deaths that occur among male workers in this age group who have worked for at least 1 year in a chemical plant, 5 are due to lung cancer. We wish to determine whether there is a difference between the proportion of deaths from lung cancer in this plant and the proportion in the general population.
One criticism of studies of this type is that they are biased by the “healthy worker” effect. That is, workers in general are healthier than the general population, particularly regarding cardiovascular endpoints, which makes the proportion of deaths from noncardiovascular causes seem abnormally high.
If the proportion of deaths from ischemic heart disease (IHD) is 40% for all 15- to 64-year-old men in England and Wales, whereas 18 of the preceding 90 deaths are attributed to IHD, then answer Problem 7.33 if deaths caused by IHD are excluded from the total.
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Chapter 7 Solutions
EBK FUNDAMENTALS OF BIOSTATISTICS
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