Concept explainers
Carbon Copy (CC), the first car produced from a clone, was created from an ovarian cell taken from her generic donor, Rainbow, a calico car. The diploid nucleus from the cell was extracted and then injected into an enucleated egg. The resulting zygote was then allowed to develop in a petri dish, and the cloned embryo was implanted in the uterus of a surrogate mother cat, who gave birth to CC. CC’s surrogate mother was a tabby (see the photo below). Geneticists were very interested in the outcome of cloning a calico cat because they were not certain if the cloned cat would have patches of orange and black, just orange, or just black. Taking into account the Lyon hypothesis, explain the basis of the uncertainty. Would you expect CC to appear identical to Rainbow? Explain why or why not.
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Concepts of Genetics (11th Edition)
- For each of the following scenarios, indicate YES (it is cloning) or NO (it is not cloning). 6. ___________ Sperm taken from a male goat is combined with a female's egg in a petri dish. The resulting embryo is implanted into the female's uterus to develop 7. ___________ A sheep embryo, composed of 16 cells, is removed from the mother's uterus and separated into individual cells. Each cell is allowed to multiply, creating 16 separate embryos, which are then implanted in different female sheep to develop to maturity. 8. ___________ A cow with many desirable traits is stimulated with hormones to produce a number of egg cells. Each of these eggs is fertilized and implanted into a surrogate mother. 9. ___________ Cell nuclei from a recently deceased dog are placed into enucleated egg cells from another female dog. These egg cells are then placed into the uterus of an additional female surrogate dog, where it grows into a puppy.arrow_forwardWhen the cloned cat Carbon Copy (CC) was born , she had black patches and white patches, but completely lacked any orange patches. The knowledgeablestudents of genetics were not surprised at this outcome.Starting with the somatic ovarian cell used as the sourceof the nucleus in the cloning process, explain how this outcomeoccurred.arrow_forwardDomesticated sheep cells have a total of 54 chromosomes (versus 46 chromosomes in human cells). (a) How many separate DNA molecules are present in a sheep liver cell at the end of the G1 phase? (b) How many separate DNA molecules are present in the daughter cells after meiosis I in the ovary of the sheep? (c) How many separate DNA molecules are present in the daughter cells after meiosis II in the ovary of the sheep?arrow_forward
- Is it acceptable or not to edit the genome of human embryos to treat genetic diseases? There is a group of genetic disorders that cause fatal childhood diseases. To avoid having children with these genetic disorders, some parents choose to use a procedure called in vitro fertilization (IVF) followed by genetic testing. Typically, in the first step of IVF, women receive hormone injections to produce multiple eggs, after which the eggs are harvested. The eggs are then fertilized by sperm in a petri dish to make embryos, which are then transferred to a woman's uterus. If the goal is to identify embryos that do not have specific genetic conditions, doctors would screen the embryos before they are implanted into the woman - in other words, they would analyze the embryos' DNA to look for variants of the gene(s) that cause the genetic disorder. While the genetic testing of IVF-produced embryos has been done for decades, the procedure is controversial. The controversies include worries that…arrow_forwardA company that offers PGD terms an embryo “normal and healthy” if it has 46 chromosomes. Why is this statement misleading? , Two famous male actors had twins using a surrogate mother who carried two embryos that hadbeen fertilized in vitro, one with one man’s sperm and the other with the other man’s sperm. In terms of genetics, how closely are the babies, a boy and a girl, related to each other if they have different fathers?arrow_forwardSelect the true statements. (can be multiple). Sperm and egg cells are diploid, meaning that they have two copies of the human genome. Somatic cells are haploid, meaning that they have one copy of the human genome. Stem cells are haploid, meaning that they have one copy of the human genome. Somatic cells are diploid, meaning that they have two copies of the human genome.arrow_forward
- suppose a male human entered the Progenation Machine. Would it be possible for the machine to produce a female from his chromosomes? Why, or why notarrow_forwardFor each of the following scenarios, indicate Yes (it is cloning) or NO (it is NOT cloning) _____________________Sperm taken from a mole goat is combined with a female’s egg in a petri dish. The resulting embryo is implanted into the female’s uterus to develop. _____________________A sheep embryo, composed of 17 cells, is removed from the mother’s uterus and separated into individual cells. Each cell is allowed to multiply, creating 16 separate embryos, which are then implanted in different female sheep to develop to maturity. _____________________A cow with many desirable traits is stimulated with hormones to produce a number of egg cells. Each of these eggs is fertilized and implanted into a surrogate mother. _____________________In vitro fertilization _____________________Cell nuclei from an extinct wooly mammoth are placed into enucleated cow cells.arrow_forwarda. Manually, using a pencil, draw a cell in anaphase II from an organism in which 2n = 2 and each chromosome is metacentric. b. Given that each G1 nucleus from this organism contains 16 picograms of DNA, how many picograms of chromosomal DNA would you expect in the cell shown here?arrow_forward
- In the past, the IOC has employed two genetic sex- determination tests. The Barr body test screens for the presence of two X chromosomes. In XX somatic cells, one copy of the X chromosome condenses into a largely inactive structure called a Barr body, which can be seen using a light microscope. In more recent years, a polymerase chain reaction-based screen has been used to amplify the DNA sequence of the SRY gene, which is found only on the Y chromosome. Based on their karyotypes, what would be the outcome of these two tests for each of the four individuals? Drag the labels to indicate the presence or absence of a Barr body and the SRY gene sequence.arrow_forwardWoolly mammoths have been extinct for about 10,000 years, but we often find their well- preserved remains in Siberian permafrost. Research groups are now planning to use SCNT to resurrect these huge elephant- like mammals. No mammoth eggs have been recovered so far, so elephant eggs would be used instead. An elephant would also be the surrogate mother for the resulting embryo. The researchers may try a modified SCNT technique used to clone a mouse that had been dead and frozen for sixteen years. Ice crystals that form during freezing break up cell membranes, so cells from the frozen mouse were in bad shape. Their DNA was transferred into donor mouse eggs, and cells from the resulting embryos were fused with mouse stem cells. Four healthy clones were born from the hybrid embryos. What are some of the pros and cons of cloning an extinct animal?arrow_forwardIn the reproductive cloning of an animal, what cell type is used as the source of the genome of the cloned animal? A sperm cell An egg cell Any gamete cell A somatic (non-gamete)) cellarrow_forward
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