EBK BIOLOGY
5th Edition
ISBN: 9780100667976
Author: Maier
Publisher: YUZU
expand_more
expand_more
format_list_bulleted
Concept explainers
Textbook Question
Chapter 7, Problem 9GP
The allele BRCA2 was identified in families with unusually high rates of breast and ovarian cancer. Up to 80% of women with one copy of the BRCA2 allele develop one of these cancers in their lifetime.
a. Is BRCA2 a dominant or a recessive allele?
b. How is BRCA2 different from the typical pattern of
Expert Solution & Answer
![Check Mark](/static/check-mark.png)
Want to see the full answer?
Check out a sample textbook solution![Blurred answer](/static/blurred-answer.jpg)
Students have asked these similar questions
15. The following pedigree shows inheritance of Huntington's disease, a fatal genetic
disorder that causes neurodegeneration. Since signs and symptoms usually do not
appear until adulthood, many who are carriers may not realize their risk of passing on
the disease-causing allele. The following pedigree represents a family in which some
people are affected by Huntington's disease.
Reeessive Trit
er btmnt be
Mec
yplicalty
Hinhetee
Huntington diseases is a rare fatal, degenerative neurological disease in which individuals start to show symptoms in their 40s. It is caused by a dominant allele. Joe, a man in his 20s, just learned that his father has Huntington disease.a. What is the probability that Joe will also develop the disease?b. Joe and his new wife have been eager to start a family. What is the probability that their first child will eventually develop the disease?
In the snail Limnaea peregra, coiling of the shell is determined by the genes D for right-handed coiled shells, and d for left-handed coiled shells. The gene for the right-handed shell is dominant. However, the direction of coiling in any single individual is determined by the genotype of the maternal parent producing the egg, regardless of the progeny's genotype. Which describes this type of inheritance?
A. infectious heredity
B. maternal effect
C. dominant X-linked
D. organelle heredity
Chapter 7 Solutions
EBK BIOLOGY
Ch. 7 - What is the relationship between genotype and...Ch. 7 - Prob. 2LTBCh. 7 - Prob. 3LTBCh. 7 - Prob. 4LTBCh. 7 - Prob. 5LTBCh. 7 - Scientists have recently developed a process by...Ch. 7 - What is the physical basis for the independent...Ch. 7 - Prob. 8LTBCh. 7 - Prob. 9LTBCh. 7 - Prob. 10LTB
Ch. 7 - Prob. 1GPCh. 7 - Prob. 2GPCh. 7 - Prob. 3GPCh. 7 - Prob. 4GPCh. 7 - Pfeiffer syndrome is a dominant genetic disease...Ch. 7 - Prob. 6GPCh. 7 - A cross between a pea plant that produces round...Ch. 7 - Prob. 8GPCh. 7 - The allele BRCA2 was identified in families with...Ch. 7 - Two parents both have brown eyes, but they have...Ch. 7 - Prob. 2AAATBCh. 7 - Prob. 3AAATBCh. 7 - Prob. 1CTSCh. 7 - Prob. 2CTSCh. 7 - Prob. 3CTS
Additional Science Textbook Solutions
Find more solutions based on key concepts
Describe the role and impact of microbes on the earth.
Microbiology Fundamentals: A Clinical Approach - Standalone book
Why is it necessary to be in a pressurized cabin when flying at 30,000 feet?
Anatomy & Physiology
Why is it unlikely that two neighboring water molecules would be arranged like this?
Campbell Biology (11th Edition)
The term ‘spore’.
Biology Science Notebook
2. A gene is a segment of DNA that has the information to produce a functional product. The functional product ...
Genetics: Analysis and Principles
Describe the evolution of mammals, tracing their synapsid lineage from early amniote ancestors to true mammals....
Loose Leaf For Integrated Principles Of Zoology
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- This pedigree traces the inheritance of a rare disease in humans. a. Based on this pedigree, is the allele for this disease dominant or recessive? Explain. b. What genotypes are possible for the individuals labeled 1, 2, and 3?arrow_forwardDuchenne muscular dystrophy is sex linked and usually affects only males. Victims of the disease become progressively weaker, starting early in life.a. What is the probability that a woman whose brother has Duchenne’s disease will have an affected child?b. If your mother’s brother (your uncle) had Duchenne’s disease, what is the probability that you have received the allele?c. If your father’s brother had the disease, what is the probability that you have received the allele?arrow_forwardSickle cell anemia is an inherited red blood cell disorder in which there are not enough healthy red blood cells to carry oxygen throughout the body. The allele that causes sickle-cell anemia is autosomal recessive (s), and the dominant allele can be represented by S. How many offspring will be affected by the disorder if the mother is a carrier, and the father appears to be normal? (Include the gender) a. b. How many will become carriers? (include the gender) A- 三三三 四 四 II !!arrow_forward
- Achondroplasia is a form of dwarfism in humans. It is caused by a mutant allele of the fibroblast growth factor receptor 3 gene ( FGFR3) that produces an overactive protein. Having one copy of the mutant allele results in dwarfism. Two copies of the mutant allele results in death before birth. The mutant FGFR3 allele is completely penetrant. 1. What can you infer about the inheritance of the FGFR alleles? A) The mutant FGFR3 allele is pleiotropic. B) Some achondroplastic dwarfs are heterozygous for the mutant allele and some are homozygous. C) The wild-type and mutant FGFR3 alleles are codominant. D) The mutant FGFR3 allele shows incomplete penetrance. 2. If two people with achondroplasia have a child together, what is the probability that their child will also have achondroplasia? A)0 B)1/2 C)2/3 D) 3/4 E)1arrow_forwardColor blindness in humans is controlled by an X-linked completely recessive allele (Xc), while breast cancer is controlled by an autosomal completely dominant allele, B. A color blind male, who is a heterozygote carrier for breast cancer has three children/n with a normal eyed female (whose mother was color blind), who is homozygote recessive for the breast cancer allele. What is the probability that out of three children, 2 will be color blind males, and not show breast cancer, and one will be a color blind female, who shows breast cancer?arrow_forwardPiebald spotting is a condition found in humans in which there are patches of skin that lack pigmentation. The condition results from the inability of pigment-producing cells to migrate properly during development. Two adults with piebald spotting have one child who has this trait and a second child with normal skin pigmentation. a. Is the piebald spotting trait dominant or recessive? What information led you to this answer?arrow_forward
- Tay–Sachs disease is caused by recessive alleles on anautosome. In which case(s) could two parents with anormal phenotype have a child with Tay–Sachs?a. Both parents are homozygous for a Tay–Sachs allele.b. Both parents are heterozygous for a Tay–Sachsallele.c. One parent is homozygous for a Tay–Sachs allele,and the other is heterozygous.arrow_forwardSickle cell anemia is a human genetic disorder caused by an autosomal recessive allele. A couple plan to marry and want to know the probability that they will have an affected child. With your knowledge of Mendelian inheritance, what can you tell them if (1) each has one affected parent and a parent with no family history of SCA or (2) the man is affected by the disorder but the woman has no family history of SCA?arrow_forwardIn 1995, doctors reported a Chinese family in whichretinitis pigmentosa (progressive degeneration of theretina leading to blindness) affected only males. Allsix sons of affected males were affected, but all of thefive daughters of affected males (and all of thechildren of these daughters) were unaffected.a. What is the likelihood that this form of retinitispigmentosa is due to an autosomal mutationshowing complete dominance?b. What other possibilities could explain the inheritance of retinitis pigmentosa in this family? Whichof these possibilities do you think is most likely?arrow_forward
- Piebald spotting is a condition found in humans inwhich there are patches of skin that lack pigmentation. The condition results from the inability ofpigment-producing cells to migrate properly duringdevelopment. Two adults with piebald spotting haveone child who has this trait and a second child withnormal skin pigmentation.a. Is the piebald spotting trait dominant or recessive?What information led you to this answer?b. What are the genotypes of the parents?arrow_forwardEctrodactyly is a rare condition in which the fingers are absent and the hand is split. This condition is usually inherited as an autosomal dominant trait. Ademar Freire-Maia reported the appearance of ectrodactyly in a family in São Paulo, Brazil, whose pedigree is shown here. Is this pedigree consistent with autosomal dominant inheritance? If not, what mode of inheritance is most likely? Explain your reasoning.arrow_forwardTay-Sachs disease is a rare human disease in which toxic substances accumulate in nerve cells. The recessive allele responsible for the disease is inherited in a simple Mendelian manner. For unknown reasons, the allele is more common in populations of Ashkenazi Jews of eastern Europe. A woman is planning to marry her first cousin, but the couple discovers that their shared grandfather’s sister died in infancy of Tay-Sachs disease.a. Draw the relevant parts of the pedigree, and show all the genotypes as completely as possible. b. What is the probability that the cousins’ first child will have Tay-Sachs disease, assuming that all people who marry into the family are homozygous normal?arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education
![Text book image](https://www.bartleby.com/isbn_cover_images/9780134580999/9780134580999_smallCoverImage.gif)
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
![Text book image](https://www.bartleby.com/isbn_cover_images/9781947172517/9781947172517_coverImage_Textbooks.gif)
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
![Text book image](https://www.bartleby.com/isbn_cover_images/9781259398629/9781259398629_smallCoverImage.gif)
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
![Text book image](https://www.bartleby.com/isbn_cover_images/9780815344322/9780815344322_smallCoverImage.gif)
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
![Text book image](https://www.bartleby.com/isbn_cover_images/9781260159363/9781260159363_smallCoverImage.gif)
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
![Text book image](https://www.bartleby.com/isbn_cover_images/9781260231700/9781260231700_smallCoverImage.gif)
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education
How to solve genetics probability problems; Author: Shomu's Biology;https://www.youtube.com/watch?v=R0yjfb1ooUs;License: Standard YouTube License, CC-BY
Beyond Mendelian Genetics: Complex Patterns of Inheritance; Author: Professor Dave Explains;https://www.youtube.com/watch?v=-EmvmBuK-B8;License: Standard YouTube License, CC-BY