Biology: Science for Life with Physiology (5th Edition)
Biology: Science for Life with Physiology (5th Edition)
5th Edition
ISBN: 9780321922212
Author: Colleen Belk, Virginia Borden Maier
Publisher: PEARSON
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Chapter 7, Problem 9GP

The allele BRCA2 was identified in families with unusually high rates of breast and ovarian cancer. Up to 80% of women with one copy of the BRCA2 allele develop one of these cancers in their lifetime.

a. Is BRCA2 a dominant or a recessive allele?

b. How is BRCA2 different from the typical pattern of Mendelian inheritance?

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15. The following pedigree shows inheritance of Huntington's disease, a fatal genetic disorder that causes neurodegeneration. Since signs and symptoms usually do not appear until adulthood, many who are carriers may not realize their risk of passing on the disease-causing allele. The following pedigree represents a family in which some people are affected by Huntington's disease. Reeessive Trit er btmnt be Mec yplicalty Hinhetee
Huntington diseases is a rare fatal, degenerative neurological disease in which individuals start to show symptoms in their 40s. It is caused by a dominant allele. Joe, a man in his 20s, just learned that his father has Huntington disease.a. What is the probability that Joe will also develop the disease?b. Joe and his new wife have been eager to start a family. What is the probability that their first child will eventually develop the disease?
This pedigree traces the inheritance of a rare disease in humans. a. Based on this pedigree, is the allele for this disease dominant or recessive? Explain. b. What genotypes are possible for the individuals labeled 1, 2, and 3?

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How to solve genetics probability problems; Author: Shomu's Biology;https://www.youtube.com/watch?v=R0yjfb1ooUs;License: Standard YouTube License, CC-BY
Beyond Mendelian Genetics: Complex Patterns of Inheritance; Author: Professor Dave Explains;https://www.youtube.com/watch?v=-EmvmBuK-B8;License: Standard YouTube License, CC-BY