Organic Chemistry (9th Edition)
9th Edition
ISBN: 9780321971371
Author: Leroy G. Wade, Jan W. Simek
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Concept explainers
Textbook Question
Chapter 7.17B, Problem 7.33P
Predict the products and mechanisms of the following reactions. When more than one product or mechanism is possible explain which are most likely
- a. 1 - bromohexane — sodium ethoxide in ethanol
- b. 2-chlorohexane + NaOCH3 in methanol
- c. 2-chloro-2-methylbutane+NaOCH2CH3 in ethanol
- d. 2-chloro-2-methylbutane heated in ethanol
- e. isobutylchloride+KOH in ethanol/water
- f. isobutylchloride + AgNO3 in ethanol/water
- g. 1– bromo – 1 – methylcyclopentane + NaOEt in ethanol
- h. 1-bromo-1-methylcyclopentane heated in methanol
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
Draw Out Your Predictions of This Reaction:
Part A: S-2-chlorohexane + NaOCH3NaOCH3 in methanol. (There are three elimination products and one substitution product.)
Part B: 2-chloro-2-methylbutane heated in ethanol
Choose the best reagents from the list provided below for carrying out the following conversion. Match the reagent with the step number.
HCl (aq), Zn(Hg)
KMnO4, H3O+
CH3Cl, AlCl3
HNO3, H2SO4
Cl2, FeCl3
fuming sulfuric acid
Say the type of reaction (SN1, SN2, E1 or E2) and detail the mechanism:
1-chloro-1,2-dimethylcyclohaxane + sodium methoxide in methanol.
Chapter 7 Solutions
Organic Chemistry (9th Edition)
Ch. 7.3A - Prob. 7.1PCh. 7.3A - Prob. 7.2PCh. 7.3B - Draw five more compounds of formula C4H6NOC1.Ch. 7.3B - For each of the following molecular formulas,...Ch. 7.4 - Give the systematic (IUPAC) names of the following...Ch. 7.5B - The following names are all incorrect. Draw the...Ch. 7.5B - Prob. 7.8PCh. 7.5B - a. How many stereogcmc double bonds are in...Ch. 7.6 - Teflon-coated frying pans routinely endure...Ch. 7.7B - Prob. 7.11P
Ch. 7.8B - Use the data in Table7-2 to predict the energy...Ch. 7.8C - Prob. 7.13PCh. 7.8E - Explain why each of the following alkenes is...Ch. 7.8F - Prob. 7.15PCh. 7.10 - Prob. 7.16PCh. 7.10A - SN1 substitution and E1 elimination frequently...Ch. 7.10C - Prob. 7.18PCh. 7.10C - Prob. 7.19PCh. 7.10C - Prob. 7.20PCh. 7.11 - Prob. 7.21PCh. 7.11 - Prob. 7.22PCh. 7.12 - Prob. 7.23PCh. 7.12 - Prob. 7.24PCh. 7.13 - Prob. 7.25PCh. 7.14B - Prob. 7.26PCh. 7.14B - Make models of the blowing compounds, and predict...Ch. 7.15 - Prob. 7.28PCh. 7.15 - Prob. 7.29PCh. 7.15 - Prob. 7.30PCh. 7.15 - Prob. 7.31PCh. 7.16 - Predict the major and minor elimination products...Ch. 7.17B - Predict the products and mechanisms of the...Ch. 7.18 - Propose mechanisms for the following reactions.Ch. 7.18 - Prob. 7.35PCh. 7.19B - The dehydrogenation of butane to trans-but-2-ene...Ch. 7.19B - Prob. 7.37PCh. 7.19B - Prob. 7.38PCh. 7.19B - Prob. 7.39PCh. 7 - Prob. 7.40SPCh. 7 - Prob. 7.41SPCh. 7 - Prob. 7.42SPCh. 7 - Prob. 7.43SPCh. 7 - Prob. 7.44SPCh. 7 - Prob. 7.45SPCh. 7 - Prob. 7.46SPCh. 7 - The energy difference between cis- and...Ch. 7 - Prob. 7.48SPCh. 7 - Prob. 7.49SPCh. 7 - Prob. 7.50SPCh. 7 - What halides would undergo E2 dehydrohalogenation...Ch. 7 - Prob. 7.52SPCh. 7 - Prob. 7.53SPCh. 7 - Write a balanced equation for each reaction,...Ch. 7 - Prob. 7.55SPCh. 7 - Using cyclohexane as your starting material, show...Ch. 7 - Show how you would prepare cyclopentene from each...Ch. 7 - Prob. 7.58SPCh. 7 - E1 eliminations of alkyl halides are rarely useful...Ch. 7 - Prob. 7.60SPCh. 7 - Propose mechanisms for the following reactions....Ch. 7 - Prob. 7.62SPCh. 7 - Prob. 7.63SPCh. 7 - Prob. 7.64SPCh. 7 - Prob. 7.65SPCh. 7 - Prob. 7.66SPCh. 7 - Prob. 7.67SPCh. 7 - Prob. 7.68SPCh. 7 - Prob. 7.69SPCh. 7 - Explain the dramatic difference in rotational...Ch. 7 - One of the following dichloronorbornanes undergoes...Ch. 7 - A graduate student wanted to make...Ch. 7 - Prob. 7.73SPCh. 7 - Prob. 7.74SPCh. 7 - Prob. 7.75SPCh. 7 - Prob. 7.76SP
Additional Science Textbook Solutions
Find more solutions based on key concepts
Draw a Lewis structure for each of the following species: a. H2CO3 b. CO32 c. CH2O d. CO2
Essential Organic Chemistry (3rd Edition)
4. 38 Strontium has four naturally occurring isotopes, with mass numbers 84, 86, 87, arid 88.
a. Write the atom...
General, Organic, and Biological Chemistry: Structures of Life (5th Edition)
4. 38 Strontium has four naturally occurring isotopes, with mass numbers 84, 86, 87, arid 88.
a. Write the atom...
Basic Chemistry (5th Edition)
Write a Lewis formula for each of the following organic molecules: C2H3Cl (vinyl chloride: starting material fo...
Organic Chemistry - Standalone book
Label each statement about the polynucleotide ATGGCG as true or false. The polynucleotide has six nucleotides. ...
General, Organic, & Biological Chemistry
Practice Exercise 1
Which of the following factors determines the size of an atom? a. the volume of the nucleus...
Chemistry: The Central Science (14th Edition)
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.Similar questions
- Organic chemistry student Everett has set up two separate electrophilic addition reactions with 2-butyne (shown below). In reaction (i) the alkyne is treated with 1 equivalent of HBr, which successful provides (Z)-2-bromo-2-butene. In reaction (ii) the alkyne is subjected to a two-step hydroboroation/oxidation sequence. Interestingly, Everett’s second reaction fails to provide the desired methyl ketone and instead has provided butan-2,3-diol. (a) Provide the structure of intermediate X form the first step of reaction (ii). (b) Briefly explain (use structures if necessary) why reaction (i) provided an alkene where as reaction (ii) provided an alkane when only 1 equivalent of the electrophile was used in each reaction.arrow_forwardPredict the products and mechanisms of the following reactions. When more than oneproduct or mechanism is possible, explain which are most likely.(a) 1@bromohexane + sodium ethoxide in ethanolarrow_forwardPredict the products and mechanisms of the following reactions. When more than oneproduct or mechanism is possible, explain which are most likely.(a) 1@bromohexane + sodium ethoxide in ethanol(b) 2@chlorohexane + NaOCH3 in methanolarrow_forward
- The two Grignard reactions and the reduction reaction below are all believed to have similar mechanisms. Use the curved arrow formalism to draw a single mechanism for these reactions using :Nuc-1 to indicate the nucleophile. The reacations are: cyclohexylmagnesium chloride + acetone in ether --> 2-cyclohexyl-2-propanol phenylmagnesium bromide + acetone in ether --> 2-phenyl-2-propanol Acetone + NaBH4 --> 2-propanolarrow_forwardThe sodium iodide test is used to identify primary alkyl halides and it also takes place via a substitution reaction.Describe the test including the reactions that explain the full mechanism. Explain whether this reaction follows aSN1 or a SN2 mechanism.arrow_forwardWrite what the products A, B, C, D, E, F, G, H, I, J and K are in the reactions below.arrow_forward
- Predict the products and mechanisms of the following reactions. When more than oneproduct or mechanism is possible, explain which are most likely.(a) 1@bromohexane + sodium ethoxide in ethanoarrow_forwardIn this study, the researcher compared S N 2 and E2reaction rates for four substrates. Three of the substrates had a second halogen on the bposition in the molecule. This work also compared the behavior of two nucleophiles:dianion I and II. You should read the abstract and look at Scheme 1 (p. 3082) and Table 4(p. 3086). Abstract: The gas-phase reactions of benzoate and phenolate containing dianions with a series of ‚-substitutedalkyl bromides (X-CH2CH2Br, X ) H, F, Cl, Br) have been studied in a quadrupole ion trap mass spectrometer.Branching ratios between SN 2 and E2 products were measured and rate constants were determined. The‚-halogens increase both the S N 2 and E2 rates, but the effect is greater for the latter process and thereforethese substituents lead to an increase in the amount of elimination. The kinetic data for the SN 2 reactions canbe analyzed via a two-parameter, linear free-energy relationship and the results indicate that field-effects (i.e.,electron-withdrawing…arrow_forwardIn this study, the researcher compared S N 2 and E2reaction rates for four substrates. Three of the substrates had a second halogen on the bposition in the molecule. This work also compared the behavior of two nucleophiles:dianion I and II. You should read the abstract and look at Scheme 1 (p. 3082) and Table 4(p. 3086). Abstract: The gas-phase reactions of benzoate and phenolate containing dianions with a series of ‚-substitutedalkyl bromides (X-CH2CH2Br, X ) H, F, Cl, Br) have been studied in a quadrupole ion trap mass spectrometer.Branching ratios between SN 2 and E2 products were measured and rate constants were determined. The‚-halogens increase both the S N 2 and E2 rates, but the effect is greater for the latter process and thereforethese substituents lead to an increase in the amount of elimination. The kinetic data for the SN 2 reactions canbe analyzed via a two-parameter, linear free-energy relationship and the results indicate that field-effects (i.e.,electron-withdrawing…arrow_forward
- In this study, the researcher compared S N 2 and E2reaction rates for four substrates. Three of the substrates had a second halogen on the bposition in the molecule. This work also compared the behavior of two nucleophiles:dianion I and II. You should read the abstract and look at Scheme 1 (p. 3082) and Table 4(p. 3086). Abstract: The gas-phase reactions of benzoate and phenolate containing dianions with a series of ‚-substitutedalkyl bromides (X-CH2CH2Br, X ) H, F, Cl, Br) have been studied in a quadrupole ion trap mass spectrometer.Branching ratios between SN 2 and E2 products were measured and rate constants were determined. The‚-halogens increase both the S N 2 and E2 rates, but the effect is greater for the latter process and thereforethese substituents lead to an increase in the amount of elimination. The kinetic data for the SN 2 reactions canbe analyzed via a two-parameter, linear free-energy relationship and the results indicate that field-effects (i.e.,electron-withdrawing…arrow_forward] The reaction of 2-bromopropane and sodium ethoxide in ethanol reacts 6.7 times faster than 2-bromo-1-deuteriopropane under the same conditions. Explain what mechanism this data is consistent with, and whyarrow_forwardSay the type of reaction (SN1, SN2, E1 or E2) and detail the mechanism: 4-bromo-2-ethyl-2-pentene + methanolarrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Organic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning
Organic Chemistry
Chemistry
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:Cengage Learning
Coenzymes and cofactors; Author: CH15 SWAYAM Prabha IIT Madras;https://www.youtube.com/watch?v=bubY2Nm7hVM;License: Standard YouTube License, CC-BY
Aromaticity and Huckel's Rule; Author: Professor Dave Explains;https://www.youtube.com/watch?v=7-BguH4_WBQ;License: Standard Youtube License