Campbell Essential Biology (6th Edition) - standalone book
6th Edition
ISBN: 9780133917789
Author: Eric J. Simon, Jean L. Dickey, Jane B. Reece, Kelly A. Hogan
Publisher: PEARSON
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Textbook Question
Chapter 8, Problem 11SQ
Although nondisjunction is a random event, there are many more people with an extra chromosome 21, which causes Down syndrome, than people with an extra chromosome 3 or chromosome 16. Explain.
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A phenotypically normal boy has 45 chromosomes, but his sister, who has Down syndrome, has 46. Suggest an explanation that explains both children.
In general, why do changes in chromosome structure or numbertend to affect an individual’s phenotype? Explain why somechanges in chromosome structure, such as reciprocal translocations,do not.
Two phenotypically unaffected parents produce two children withfamilial Down syndrome. With regard to chromosomes 14 and 21,what are the chromosomal compositions of the parents?
Chapter 8 Solutions
Campbell Essential Biology (6th Edition) - standalone book
Ch. 8 - Which of the following is not a function of...Ch. 8 - In what sense are the daughter cells produced by...Ch. 8 - Why is it hard to observe individual chromosomes...Ch. 8 - A biochemist measures the amount of DNA in cells...Ch. 8 - What phases of mitosis are opposite in terms of...Ch. 8 - Complete the following table to compare mitosis...Ch. 8 - If an intestinal cell in a dog contains 78...Ch. 8 - A micrograph of a dividing cell from a mouse shows...Ch. 8 - Prob. 9SQCh. 8 - Prob. 10SQ
Ch. 8 - Although nondisjunction is a random event, there...Ch. 8 - A mule is the offspring of a horse and a donkey. A...Ch. 8 - Prob. 13PSCh. 8 - Interpreting Data The graph shows the incidence of...Ch. 8 - If an endangered species can reproduce by...Ch. 8 - Prob. 16BSCh. 8 - The practice of buying and selling gametes,...
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- Assume that a meiotic-nondisjunction event causes trisomy 8 in a newborn. If two of the three copies of chromosome 8 are absolutely identical, at what point during meiosis did the nondisjunction event take place?arrow_forwardVariations in Chromosome NumberAneuploidy Describe the process of nondisjunction and explain when it takes place during cell division.arrow_forwardHuman sex chromosomes are XX for females and XY for males. a. With respect to an X-linked gene, how many different types of gametes can a male produce? b. If a female is homozygous for an X-linked allele, how many different types of gametes can she produce with respect to this allele? c. If a female is heterozygous for an X-linked allele, how many different types of gametes can she produce with respect to this allele?arrow_forward
- Normally you cant inherit both copies of a homologous chromosome from the same parent. Why? Assuming that no crossing over has occurred, how likely is it that one of your non-sex chromosomes is an exact copy of the same chromosome your maternal grandmother had? Explain your answer.arrow_forwardTwo phenotypically unaffected parents produce two children with familial Down syndrome. Regarding chromosome 14 and 21, what are the chromosomal composition of the parents?arrow_forwardHow does nondisjunction lead to abnormalities in chromosome number? Describe two types of genetic disorders that can result from nondisjunction.arrow_forward
- A phenotypically normal woman has an abnormally structured chromosome 2, along with a normal homologue. She marries a phenotypically normal man with an abnormally structured chromosome 16 and a normal homologue. What is the probability of their child will have an abnormal chromosome 2 and 16? What is the probability that this child, having inherited both abnormal chromosomes, will now pass both abnormal chromosomes to its children?arrow_forwardIn a sample of 1000 patients with Down syndrome, a geneticist discovers that 95% of them are trisomic, while 5% have diploid number of chromosomes. Explain this discrepancy.arrow_forwardA normal mother has translocations on chromosomes 14:21. With respect to chromosomes 14:21, how many combinations of chromosomes are possible? How many gametes are viable? If the woman has children with an normal father, what is the probability that there is a daughter with Down Syndrome or a son with an unaffected phenotype?arrow_forward
- A woman with no phenotype is known to have a 14:21 translocation. 1. With respect to only chromosomes 14 and 21, how many distinct chromosome combinations will happen in her eggs? What portion will be viable? 2. If she has children with a normal man (no translocations), what is the probability that they have a daughter with Down Syndrome or a son with no phenotype?arrow_forwarddescribe a specific example of chromosome abnormality that leads to human cancers, such as leukemia, other than the Philadelphia chromosome that is derived from the translocation of chromosome 9 and 22arrow_forwardA man who is a carrier of a translocated 15/21 chromosome marries a genotypically normal woman. (1). Show the possible gametes that will be formed by this man if the translocated 15/21 chromosome synapses with chromosome 21 at Prophase I. (2). What is the probability that the first child of the couple will be a phenotypically normal girl? (3). What is the probability that the first child of the couple will be a genetically normal boy?arrow_forward
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