Concepts of Genetics (11th Edition)
11th Edition
ISBN: 9780321948915
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Textbook Question
Chapter 8, Problem 30ESP
A 3-year-old child exhibited some early indication of Turner syndrome, which results from a 45,X chromosome composition. Karyotypic analysis demonstrated two cell types: 46,XX (normal) and 45,X. Propose a mechanism for the origin of this mosaicism.
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A chromosome of genotype C D recombines with a homolog of genotype c d during meiosis when Spo11 produces a double-strand break between genes C and D. If anticrossover helicase disentangles the invading strand, the likely outcome would be
A) two C D and two c d gametes. B) two C d and two c D gametes. C) one C D, one C d, one c D, and one c d gamete. D) four C D gametes. E) four c d gametes
Explain how mitotic recombination leads to the mosaiccondition termed twin spots.
An individual is heterozygous for a reciprocal translocation, with the following chromosomes:
A • B C D E F
A • B C V W X
R ST • U D E F
R ST • U V W X
Q. Draw the products of alternate, adjacent-1, and adjacent-2 segregations.
Chapter 8 Solutions
Concepts of Genetics (11th Edition)
Ch. 8 - A human female with Turner syndrome (47, X) also...Ch. 8 - When two plants belonging to the same genus but...Ch. 8 - What is the effect of a rare double crossover (a)...Ch. 8 - Prob. 1CSCh. 8 - Prob. 2CSCh. 8 - Aquatic vegetation overgrowth, usually controlled...Ch. 8 - HOW DO WE KNOW? In this chapter, we have focused...Ch. 8 - Review the Chapter Concepts list on page 171....Ch. 8 - Define these pairs of terms, and distinguish...Ch. 8 - For a species with a diploid number of 18,...
Ch. 8 - What evidence suggests that Down syndrome is more...Ch. 8 - What evidence indicates that humans with aneuploid...Ch. 8 - Contrast the fertility of an allotetraploid with...Ch. 8 - Describe the origin of cultivated American cotton.Ch. 8 - Predict how the synaptic configurations of...Ch. 8 - Inversions are said to suppress crossing over. Is...Ch. 8 - Contrast the genetic composition of gametes...Ch. 8 - Human adult hemoglobin is a tetramer containing...Ch. 8 - Discuss Ohnos hypothesis on the role of gene...Ch. 8 - What roles have inversions and translocations...Ch. 8 - The primrose, Primula kewensis, has 36 chromosomes...Ch. 8 - Certain varieties of chrysanthemums contain 18,...Ch. 8 - Drosophila may be monosomic for chromosome 4, yet...Ch. 8 - Mendelian ratios are modified in crosses involving...Ch. 8 - Having correctly established the F2 ratio in...Ch. 8 - The mutations called bobbed in Drosophila result...Ch. 8 - The outcome of a single crossover between...Ch. 8 - A couple planning their family are aware that...Ch. 8 - In a cross in Drosophila, a female heterozygous...Ch. 8 - A woman who sought genetic counseling is found to...Ch. 8 - Prob. 25ESPCh. 8 - In a recent cytogenetic study on 1021 cases of...Ch. 8 - A boy with Klinefelter syndrome (47,XXY) is born...Ch. 8 - Prob. 28ESPCh. 8 - Prob. 29ESPCh. 8 - A 3-year-old child exhibited some early indication...Ch. 8 - A normal female is discovered with 45 chromosomes,...Ch. 8 - Prob. 32ESP
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- Genes R, H and F are located on the same chromosome. On one chromosome R, h and f alleles are attached, while on the homologue contains r, H and F. Which of the following would be an example of a recombination event?arrow_forwardTwo strains of S. cerevisae (yeast) are crossed. One has the genotype A B and the other a b. Which statement correctly describes the tetrads that can be produced by one reciprocal exchange between the A and B genes without gene conversion in the dihybrid? A) Recombination occurs at the four-strand stage to produce a tetrad with A B, A B, a B, and a b chromosomes. B) Recombination occurs at the four-strand stage to produce a tetrad with A B, A b, a B, and a b chromosomes. C) Recombination occurs at the two-strand stage to produce a tetrad with A B, A b, a B, and a b chromosomes. D) Recombination occurs at the two-strand stage to produce a tetrad with A b, A b, a B, and a B chromosomes.arrow_forwardA colleague e-mails you saying that she has identified an interesting chromosome variation at 21q13. In discussing this discovery with a friend who is not a cytogeneticist, explain how you would describe this location, defining each term in the chromosome address 21q13.arrow_forward
- An individual heterozygous for a reciprocal translocation possesses the following chromosomes: A B • C D E F G A B • C D V W X R S • T U E F G R S • T U V W X Q. Give the products that result from alternate, adjacent-1, and adjacent-2 segregation.arrow_forwardDiscuss the principles of the chromosome theory of inheritance. Which principles were deducedvia light microscopy, and which were deduced from crosses? What modern techniques couldbe used to support the chromosome theory of inheritance?arrow_forwardConstruct a chromosome map from the following charts showing crossover frequencies for linkage groups on autosomes. (this one is tricky due to the unusual recombinations Gene Combinations Recombination Frequency y/w 2.2 v/m 3.0 v/r 26.6 v/w 30.0 v/y 32.2 w/m 33.0 y/m 35.2 w/r 56.6arrow_forward
- Construct a map of the chromosome, with the most accurate map distances, from the following recombination frequencies between individual pairs of genes: C –F 13%, V –F 20%, V –C 8%, S –F 4%, C –S 9%,arrow_forwardThis karyotype is from a baby that was born alive but died shortly after birth. What condition is observed from this karyotype?arrow_forwardA geneticist determines that the order of four genes on a specific chromosome is CABD because the recombination frequencies were 35% for C-D, 24% for A-D, 23% for B-D, and 10% for A-B. What has the geneticist constructed?arrow_forward
- In your own words, explain why a testcross cannot produce more than 50% recombinant offspring. When a testcross does produce 50% recombinant offspring, what does this result mean?arrow_forwardIn Creighton and McClintock’s experiment demonstrating thatcrossing over involves physical exchange between chromosomes, explain the importance of the cytological markers(the translocated segment and the chromosome knob) in theexperimental rationale.arrow_forwardWhich type(s) of chromosomal aberrations will suppress recombination in heterozygotes? A.) paracentric inversion B.)pericentric inversion C.)Robertsonian translocation D.)reciprocal translocation E.)tandem duplicationarrow_forward
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