Essentials of Genetics (9th Edition) - Standalone book
9th Edition
ISBN: 9780134047799
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Textbook Question
Chapter 9, Problem 16PDQ
What might Watson and Crick have concluded, had Chargaff's data from a single source indicated the following base composition?
| A | T | G | C | |
| % | 29 | 19 | 21 | 31 |
Why would this conclusion be contradictory to Wilkins and Franklin's data?
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You have a sample of genetic material. The nitrogenous base content is 29% guanine.
a) If the sample is DNA, what are the amounts of the other bases? Explain your thought process
b) Why can you not determine the amounts of the other bases if the sample is RNA? Explain your answer
c) How did Watson and Crick make use the relationships between base pairs as they constructed the model for DNA?
With regard to Chargaff’s experiment described in Figure shown,answer the following:A. What is the purpose of paper chromatography?B. Explain why it is necessary to remove the bases in order todetermine the base composition of DNA.C. Would Chargaff’s experiments have been convincing if theyhad been done on DNA from only one species? Discuss.
Number of hydrogen bonds that form between U and A in a Watson-Crick base pair interactions?a) 0b) 1c) 2d) 3
Chapter 9 Solutions
Essentials of Genetics (9th Edition) - Standalone book
Ch. 9 - CASE STUDY |Zigs and zags of the smallpox virus...Ch. 9 -
CASE STUDY | Zigs and zags of the smallpox...Ch. 9 - CASE STUDY | Zigs and zags of the smallpox...Ch. 9 - CASE STUDY | Zigs and zags of the smallpox virus...Ch. 9 -
HOW DO WE KNOW?
1. In this chapter, we have...Ch. 9 - Review the Chapter Concepts list on p. 160. Most...Ch. 9 - Discuss the reasons why proteins were generally...Ch. 9 -
4. Contrast the various contributions made to our...Ch. 9 - When Avery and his colleagues had obtained what...Ch. 9 - Why were 32P and 35S chosen in the Hershey–Chase...
Ch. 9 - Does the design of the Hershey-Chase experiment...Ch. 9 - What observations are consistent with the...Ch. 9 - What are the exceptions to the general rule that...Ch. 9 -
10. Draw the chemical structure of the three...Ch. 9 - How are the carbon and nitrogen atoms of the...Ch. 9 - Adenine may also be named 6–amino purine. How...Ch. 9 -
13. Draw the chemical structure of a dinucleotide...Ch. 9 - Describe the various characteristics of the...Ch. 9 - Prob. 15PDQCh. 9 - What might Watson and Crick have concluded, had...Ch. 9 - Prob. 17PDQCh. 9 - Prob. 18PDQCh. 9 - Prob. 19PDQCh. 9 - Prob. 20PDQCh. 9 - Prob. 21PDQCh. 9 - Prob. 22PDQCh. 9 -
23. Why is Tm related to base composition?
Ch. 9 - What is the chemical basis of molecular...Ch. 9 - What did the Watson–Crick model suggest about the...Ch. 9 - A genetics student was asked to draw the chemical...Ch. 9 - Prob. 27PDQCh. 9 -
28. One of the most common spontaneous lesions...Ch. 9 - Prob. 29PDQCh. 9 - Prob. 30PDQCh. 9 - Prob. 31PDQCh. 9 -
32. During electrophoresis, DNA molecules can...Ch. 9 - Assume that you are interested in separating short...
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- Chemical analysis shows that a nucleic acid sample contains A, U, C, and G. Is this DNA or RNA? Why?arrow_forwardState the properties of the WatsonCrick model of DNA in the following categories: a. number of polynucleotide chains b. polarity (running in same direction or opposite directions) c. bases on interior or exterior of molecule d. sugar/phosphate on interior or exterior of molecule e. which bases pair with which f. right- or left-handed helixarrow_forwardThe image below was the basis of Watson and Crick to be able to elucidate the DNA structure. Explain/Discuss the meaning of this image as seen by Watson and Crick and how was it able to support the present-day structure of the Watson and Crick DNA?arrow_forward
- IF A DOUBLE-STRAND DNA SAMPLE WAS COMPOSED OF 10 PERCENT THYMINE, WHAT WOULD BE THE PERCENTAGE OF GUANINE?arrow_forwardWhich of the following statements DOES NOT apply to the Watson and Crick model of DNA? a. The two strands of the DNA helix are anti-parallel. b. The distance between the strands of the helix is 20 angstroms (A). c. The framework of the helix consists of sugar-phosphate units of the nucleotides. d. The two strands of the helix are held together by covalent bonds. e. The purines are attracted to the pyrimidines. ...Explain your answer.arrow_forwardWhile trying to determine the structure of DNA, Watson and Crick at one point proposed that like bases are bonded to like bases. For example, thymine would be bonded to thymine, cytosine would be bonded to cytosine, and so on. Explain why this proposed model would not fit based on what was discovered to be true about DNA.arrow_forward
- What were the two critical questions about genetic material in cells that Watson and Crick answered with the double heliz and how did the double heliz structure answer each question?arrow_forwardIf you tiled a floor with the planar rings from the bases of all the DNA molecules of living creatures on Earth, approximately how many times could you cover the Earth’s surface? This is meant to be an estimation/Fermi problem so it does not have to be exact.arrow_forwardWhat evidence did Watson and Crick have at their disposal in 1953? What was their approach in arriving at the structure of DNA?arrow_forward
- To carry out sequencing, you need to include 600 ng of DNA and a total of 6.4 pmol of sequencing primer. If your concentration of DNA (determined by A260 reading on a Nanodrop Spectrophotometer) is 89.0 ng/μL, how many μL of this sample do you need for a total of 600 ng?arrow_forwardAt that time, why did it seem reasonable for the bases to be on the outside of the DNA molecule and what evidence caused Watson and crick to revise this model?arrow_forwardIn samples of DNA isolated from two unidentified species of bacteria, X andY, adenine makes up 32% and 17%, respectively, of the total bases. Whatrelative proportions of adenine, guanine, thymine, and cytosine would youexpect to find in the two DNA samples? What assumptions have you made?One of these species was isolated from a hot spring (64 °C). Which species ismost likely the thermophilic bacterium, and why?arrow_forward
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