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Concept explainers
Interpretation:
The motive behind the 10K genome project.
Concept introduction:
The genome project is an attempt to sequence the entire genome of an organism. The human genome project or HGP is one such project that started formally in 1990 and was an effort to sequence the entire genome of a human, which consists of some 3.3 billion base pairs that are spread over 23 pairs of chromosomes.
The results suggested that a human consists of only 30,000 genes and this number gradually decreases to fewer than 25,000 genes. It was important as the genes that determine a genetic trait or are responsible for a disease could be identified and the information derived can be used to develop new ways to treat diseases.
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Chapter 9 Solutions
Bundle: Biochemistry, Loose-leaf Version, 9th + Owlv2,1 Term Printed Access Card
- RECALL What would be an advantage of using HaeIII for a cloning experiment? What would be a disadvantage?arrow_forwardREFLECT AND APPLY Why is a short RNA primer needed for replication?arrow_forwardREFLECT AND APPLY The genes for both the a- and b-globin chains of hemoglobin contain introns (i.e., they are split genes). How would this fact affect your plans if you wanted to introduce the gene for a-globin into a bacterial plasmid and have the bacteria produce a-globin?arrow_forward
- REFLECT AND APPLY Why is it more important for DNA to be replicated accurately than transcribed accurately?arrow_forwardREFLECT AND APPLY List three mechanisms that relax the twisting stress in helical DNA molecules.arrow_forwardREFLECT AND APPLY Diagram a section of DNA being transcribed. Give the various names for the two strands of DNA.arrow_forward
- REFLECT AND APPLY One of the original structures proposed for DNA had all the phosphate groups positioned at the center of a long fiber. Give a reason why this proposal was rejected.arrow_forwardREFLECT AND APPLY (a) Is it biologically advantageous that DNA is stable? Why or why not? (b) Is it biologically advantageous that RNA is unstable? Why or why not?arrow_forwardRECALL What is blue/white screening? What is the key feature of a plasmid that is used for it?arrow_forward
- REFLECT AND APPLY What role does an operon play in the synthesis of enzymes in prokaryotes?arrow_forwardREFLECT AND APPLY Describe the recognition process by which the tRNA for N-formylmethionine interacts with the portion of mRNA that specifies the start of transcription.arrow_forwardBIOCHEMICAL CONNECTIONS What is a riboswitch?arrow_forward
- BiochemistryBiochemistryISBN:9781305961135Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougalPublisher:Cengage Learning
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