Concepts of Genetics (12th Edition)
Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 9, Problem 4NST
Summary Introduction

To explain: The phenomenon of the reduced mutation rate of mitochondrial DNA over generations.

Introduction: Mitochondria are inherited through the cytoplasm of mother in most organisms. Mitochondria carry their own DNA (deoxyribonucleic acid) and  information about the genetic expression.

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Deletions in the mitochondrial DNA can result in parasitic mitochondria which do not respire but reproduce faster than normal mitochondria in a yeast cell.  However, yeast cells that harvest energy only through fermentation multiply less slowly and have decreased fitness. When yeast cells containing varying populations of parasitic and normal mitochondria are grown in cultures with different cell densities over several generations, it is expected that    A. normal mitochondria will be rare in large yeast cell populations. B. averaged across populations, yeast cells with normal mitochondria remained at intermediate levels. C.  parasitic mitochondria will be rare in large yeast cell populations. D. parasitic mitochondria will be rare in small yeast cell populations.
All mutations in mitochondrial genes ultimately affect (whether directly or indirectly) the key function of mitochondria, which is to make ATP. Why then do mutations in different genes cause different diseases, with specific symptoms?
Explain the likely evolutionary origin of mitochondrial and chloroplast genomes. How have the sizes of the mitochondrial and chloroplast genomes changed since their origin? How has thisoccurred?

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Concepts of Genetics (12th Edition)

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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY