CAMPBELL BIOLOGY IN FOCUS-W/MASTR.BIO.
3rd Edition
ISBN: 9780134875040
Author: Urry
Publisher: PEARSON
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Textbook Question
Chapter 9, Problem 5TYU
The drug cytochalasin B blocks the function of actin. Which of the following aspects of the animal cell cycle would be most disrupted by cytochalasin B?
- A. spindle formation
- B. spindle attachment to kinetochores
- C. cell elongation during anaphase
- D. cleavage furrow formation and cytokinesis
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Students have asked these similar questions
Which of the following statements is FALSE?
A.
Centrosomes are anchor points for microtubules and are essential to form the mitotic spindle.
B.
In the eukaryotic cell cycle the cell spends much more time in the interphase than in the mitotic phase.
C.
In telophase two nuclear envelopes are fully formed and the cell splits in two via cytokinesis.
D.
The contraction of the kinetochore microtubules leads to the separation of the sister chromatids during anaphase.
E.
In the prophase chromatin condenses into X-shaped chromosomes.
Which of the following statements about the cell cycle is TRUE?
a. The protein APC blocks cells from entering anaphase
b. CDKs are degraded after each cell cycle phase by the addition of a ubiquitin chain to the proteins
c. A kinase is a protein that adds a ubiquitin chain to other proteins Cyclin activity is necessary, but not always sufficient, for CDK activation
d. Cyclin proteins must be degraded before Cdk proteins can be activated
The diagram below shows a model for the normal regulation of the transition to
anaphase during mitosis.
1. Signals are released by
unattached kinetochores
that cause MAD to bind
CDC20.
MAD
CDC20
6. Chromatids
separate as mitosis
procoeds to anaphase.
COHESIN
3. The APCCDC20
CDC20 complex ubiquinates
Securin.
APC
2. When all kinetochores
are attached, MAD
releases CDC20 which
then combines
with APC
UBIQUITIN
SEPARASE . Separase destroys
Cohesin
APC
SEPARASE
SECURIN
4. Securin is destroyed,
releasing Separase
Your analyses of cancer cells that do not regulate this transition normally indicate that:
MAD is binding to CDC20;
• Ubiquitin is not attached to securin;
• Sister chromatids separate and move to opposite poles of the cell.
Which of the following explanations could account for all of your observations?
a. The cell has an alteration in MAD that prevents it from releasing CDC20 when the 'unattached kinetochore' signal
stops.
O b. More than one of the other answer choices are correct.…
Chapter 9 Solutions
CAMPBELL BIOLOGY IN FOCUS-W/MASTR.BIO.
Ch. 9.1 - How many chromosomes are drawn in each part of...Ch. 9.1 - WHAT IF? A chicken has 78 chromosomes in its...Ch. 9.2 - How many chromosomes are shown in the drawing in...Ch. 9.2 - Compare cytokinesis in animal cells and plant...Ch. 9.2 - Prob. 3CCCh. 9.2 - Compare the roles of tubulin and actin during...Ch. 9.3 - Prob. 1CCCh. 9.3 - Prob. 2CCCh. 9.3 - Compare and contrast a benign tumor and a...Ch. 9.3 - Prob. 4CC
Ch. 9 - Through a microscope, you can see a cell plate...Ch. 9 - In the cells of some organisms, mitosis occurs...Ch. 9 - Which of the following does not occur during...Ch. 9 - Cell A has half as much DNA as cells B, C, and...Ch. 9 - The drug cytochalasin B blocks the function of...Ch. 9 - DRAW IT Draw one eukaryotic chromosome as it would...Ch. 9 - The light micrograph shows dividing cells near the...Ch. 9 - SCIENTIFIC INQUIRY Although both ends of a...Ch. 9 - FOCUS ON EVOLUTION The result of mitosis is that...Ch. 9 - FOCUS ON INFORMATION The continuity of life is...Ch. 9 - SYNTHESIZE YOUR KNOWLEDGE Shown here are two He La...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Which of the following statements about mitosis is incorrect? a. Microtubules from the spindle poles attach to the kinetochores on the chromosomes. b. In anaphase, the spindle separates sister chromatids and pulls them apart. c. In metaphase, spindle microtubules align the chromosomes at the spindle midpoint. d. Cytokinesis describes the movement of chromosomes. e. Both the animal cell furrow and the plant cell plate form at their former spindle midpoint.arrow_forwardAttachment of the mitotic spindle fibers to the kinetochores is a characteristic of which stage of mitosis? a. prophase b. prometaphase c. metaphase d. anaphasearrow_forwardDNA or deoxyribonucleic acid is the hereditary material in humans and almost all other organisms. Nearly every cell in a person's body has the same DNA. This, in turn, replicates in the non-dividing phase of the cell cycle which is a. telophase b. cytokinesis c. metaphase d. interphasearrow_forward
- Match the following events with the stages in mitosis: chromosomal materials condenses to form compact chromosomes. alignment of chromosomes along the equator or plate with microtubules attached to poles sister chromatids for each chromosome split and move to opposite poles chromosomes are clustered at each of the poles and give way to cytokinesis A. telophase B. anaphase C. metaphase D. prophasearrow_forward1) What phase of mitosis is this? Answer: 2) What is the indicated structure 1? select one. a. chromosome b. chromosome with two sister chromatids c. centrioles/centrosome d. spindle fibres e. metaphase plate 3)If the diploid (2n) number of this cell is 8 how many chromosomes are present? 4) If the diploid (2n) number of this cell is 8 how many sister chromatids are present? 5) If the diploid (2n) number of this cell is 8 how many homologous pairs are present?arrow_forwardThe drug cytochalasin B blocks the function of actin. Which of the following aspects of the animal cell cycle would be most disrupted by cytochalasin B? Spindle attachment to kinetochores DNA synthesis Cleavage furrow formation and cytokinesis Cell elongation during anaphase Spindle formationarrow_forward
- What is necessary for a cell to pass the G2 checkpoint? a. cell has reached a sufficient size b. an adequate stockpile of nucleotides c. accurate and complete DNA replication d. proper attachment of mitotic spindle fibers to kinetochoresarrow_forwardPart of cell division is that chromosomes are moved the center of the cell and then back to the poles of each newly made daughter cell. These chromosomes are moved to the center of the cell by.. Select one: a. Myosin walking on microtubules towards the center of the cell (slow growing end of microtubule) b. Oar-like motion of myosin with microfilaments causing each half of the cell to move closer together c. kinesins walking on microtubules towards the center of the cell (fast growing end of microtubule) d. vesicles floating on microfilaments of the cortical cytoskeletonarrow_forwardWhat celluar events/processes are associated with G1,S,G2,and M phases of the cell cycle? With the phases of mitosis? Some example: A. DNA replication B. Beginning of mitosis C. Normal cell growth and function D. Breaksdown of nuclear membrane E.Separation of sister chromatids F.Alignment of chromosomes on the equator of the cell H.Triggering the compaction and condensation of chromosomes I. Attachment of microtubles to kinetochoresarrow_forward
- Animal cell division is signified by the formation of cleavage furrow as oppose to plant cells, this formation appears at what stage Select one: O a. cytokinesis b. interphase Oc. metaphase O d. prophasearrow_forwardIn a cell cycle Select one: a. DNA is replicated and passed to homologous chromosomes during interphase b. DNA is replicated and passed to daughter cells during mitotic phase c. DNA and RNA are replicated and passed to parent cells during interphase d. DNA and RNA are replicated and passed to sister chromatids during mitotic phasearrow_forwardWhich of the following occurs during metaphase II? A. The chromosomes align midway between spindle poles. B. The sister chromatids separate and move toward the spindle poles. C. Spindle microtubules attach to each sister chromatid as the nuclear envelope breaks up. D. A nuclear envelope forms around each set of chromosomes to form four haploid nuclei.arrow_forward
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