BIOLOGY
BIOLOGY
5th Edition
ISBN: 9781264104680
Author: BROOKER
Publisher: MCG
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Chapter 9.3, Problem 1CS
Summary Introduction

To explain: The reason for the development of cancer because of mutations, which obstruct GTP hydrolysis ability of Ras proteins.

Introduction: Cancer can be defined as an abnormal cellular condition that is characterized by uncontrolled cell division. This condition can result from a large number of cellular, molecular, and metabolic alterations.

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Q11: You are comparing the process of RNA splicing in an mRNA from normal and mutant cells of the same tissue. You find that the mutant mRNA is longer than the mRNA from the normal cells. Examination of the sequences of the gene encoding this mRNA reveals that there are nucleotide changes at the boundary of one of the exons in the mutant cell gene. Which of the following nucleotides would be expected to be found at the 3' end of upstream donor exons and the 5' end of downstream acceptor exons in the normal gene but not in the mutant gene? A. AG-G B. AG-AG C. CA-GA D. G-AG E. CG-G
Reflect on this “Gene therapy is still in its infancy but it is believed that as it matures it will become an effective treatment for the myriad of genetic diseases that affect humanity”
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