CAMPBELL BIOLOGY-MASTERING BIO.ACCESS
12th Edition
ISBN: 9780136486787
Author: Urry
Publisher: SAVVAS L
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Chapter 9.3, Problem 3CC
Summary Introduction
To compare: The multi-enzyme complex involved in the conversion of pyruvate to acetyl CoA with the multienzyme complex that catalyzes Step 4 of the Citric acid cycle.
Introduction:
The citric acid cycle is a cyclic
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Kinetic Parameters of Enzyme-Catalyzed Reactions
TABLE 12-1 The Values of KM, Keat, and Keat/KM for Some Enzymes and Substrates
Enzyme
Substrate
KM (M)
9.5 x 10-5
1.2 x 10-²
2.6 x 10-2
2.5 x 10-2
4.4 x 10-1
8.8 x 10-2
6.6 x 10-4
Acetylcholinesterase
Carbonic anhydrase
Catalase
Chymotrypsin
Fumarase
Urease
Acetylcholine
CO₂
HCO₁
H₂O₂
N-Acetylglycine ethyl ester
N-Acetylvaline ethyl ester
N-Acetyltyrosine ethyl ester
Fumarate
Malate
Urea
5.0 x 10-6
2.5 x 10-5
2.5 x 10-2
Keat (S-¹)
1.4 x 104
1.0 × 106
4.0 × 105
1.0 X 107
5.1 x 10-2
1.7 × 10-1
1.9 X 10²
8.0 x 10²
9.0 × 10²
1.0 X 104
Keat/KM (M¹s¹)
1.5 × 108
8.3 x 107
1.5 x 107
4.0 X 108
1.2 x 10-1
1.9
2.9 × 105
1.6 × 108
3.6 X 107
4.0 X 105
Which enzyme is the most catalytically efficient?
Which substrate does chymotrypsin bind to most tightly (assume k_₁ >> K₂)?
Is fumarate or malate a better substrate of fumarase?
Is it possible to have a kcat/KM of greater than 1 x 10⁹ M-¹ s-¹? Why or why not?
Biochemical Reactions
Using good details, compare and contrast the pairs of different biochemical reactions. Create your own comparing
and contrasting map similar to the one below to show your understanding.
Anabolism
Catabolism
First Pair
of
Describe
Describe
differences here
différences here
Reaction
Types
Describe similarities
here
Second
Describe
Pair of
differences here
Reaction
Types
Describe similarties
here
Describe
differences here
Pair of
Reaction
Describe sampar lus
heru
Types
Describe
Par of
110
Describe
differences here
Describe
différences here
Describe
differences here
What is the catalytic efficiency of Catalase ?
Table. The values of KM and kcat for some Enzymes and Substrates
Enzyme
Carbonic anhydrase
Substrate
CO2
HCO3
KM (M)
1.2 x 10-2
2.6 x 10-2
Kcat (s-1)
1.0 x 106
4.0 x 105
Catalase
H2O2
2.5 x 10-2
1.0 x 107
Urease
Urea
2.5 x 10-2
4.0 x 105
O A. 4 x 108 M-s-1
O B. 4 x 108 M-1.s-1
OC25x 10-9 M-s1
D. 2.5 x 102 M-1.s-1
OE 1.0 x 107 s1
Chapter 9 Solutions
CAMPBELL BIOLOGY-MASTERING BIO.ACCESS
Ch. 9.1 - Compare and contrast aerobic and anaerobic...Ch. 9.1 - WHAT IF? If the following redox reaction...Ch. 9.2 - Prob. 1CCCh. 9.3 - Prob. 1CCCh. 9.3 - What process in your cells produce the CO2 that...Ch. 9.3 - Prob. 3CCCh. 9.4 - Prob. 1CCCh. 9.4 - WHAT IF? In the absence of O2 as in question 1,...Ch. 9.4 - MAKE CONNECTIONS Membranes must be fluid to...Ch. 9.5 - Consider the NADH formed during glycolysis. What...
Ch. 9.5 - WHAT IF? A glucose-fed yeast cell is moved from...Ch. 9.6 - MAKE CONNECTIONS Compare the structure of a fat...Ch. 9.6 - Prob. 2CCCh. 9.6 - Prob. 3CCCh. 9.6 - Prob. 4CCCh. 9 - Describe the difference between the two processes...Ch. 9 - Which reactions in glycolysis are the source of...Ch. 9 - What molecular products indicate the complete...Ch. 9 - Briefly explain the mechanism by which ATP...Ch. 9 - Prob. 9.5CRCh. 9 - Prob. 9.6CRCh. 9 - Level 1: Knowledge/Comprehension 1. The immediate...Ch. 9 - Prob. 2TYUCh. 9 - Prob. 3TYUCh. 9 - Prob. 4TYUCh. 9 - What is the oxidizing agent in the following...Ch. 9 - When electrons flow along the electron transport...Ch. 9 - Prob. 7TYUCh. 9 - Prob. 8TYUCh. 9 - Prob. 9TYUCh. 9 - Prob. 10TYUCh. 9 - INTERPRET THE DATA Phosphofructokinase is an...Ch. 9 - DRAW IT The graph here shows the pH difference...Ch. 9 - EVOLUTION CONNECTION AIP synthases are found in...Ch. 9 - SCIENTIFIC INQUIRY In the 1930s, some physicians...Ch. 9 - WRITE ABOUT A THEME: ORGANIZATION In a short essay...Ch. 9 - SYNTHESIZE YOUR KNOWLEDGE Coenzyme Q (CoQ) is sold...
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