Concept explainers
Go online to the Mendelian Index of Man (OMIM) website. Look up the following genetic conditions and answer the questions posted about them.
a. Look up Tay-Sachs disease (TSD), OMIM number
b. Go to the “Population Genetics” section discussing the TSD gene. In few sentences, summarize the human population in which TSD is most frequently found and give the approximate frequency of heterozygous carriers for the TSD mutation in North America Jews.
c. Look up cystic fibrosis (CF), OMIM
d. Go to the “Molecular Genetics” section and describe the most common mutation of the CF gene.
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Chapter A Solutions
Pearson eText Genetic Analysis: An Integrated Approach -- Instant Access (Pearson+)
- ssign phenotypes for the F2 based on the 9 : 3 : 3 : 1 ratio. 9 A_B_ _____________ 3 A_bb _____________ 3 aaB_ _____________ 1 aabb _____________ Assign traits to the alleles Assign genotypes to the F2, F1, and P1arrow_forwardAnswer the given situation below; a. Bob says that he is healthy and has no genetic diseases such as hemophilia or Down syndrome. Therefore, he says, genetics plays little role in his life. Why do you think Bob is incorrect in his conclusion? Explain your answer.arrow_forwardGo to this link and choose 2 disorders and complete the chart https://www.genome.gov/For-Patients-and-Families/Genetic-Disordersarrow_forward
- Procedure: A. Show the possible alleles that can be found in each offspring and write the blood type for each offspring on your own table. Possible alleles from Father B A |Possible alleles from Mother B. Given the blood types of the mother and the child, identify the possible blood type of the father. On your answer sheet, copy the table below and complete the father's possible bíood type. Mother's Blood Type Father's Blood Type Child's Blood Type A A AB АВ B 20 Use the table to answer the following ques tions and list all possible blood types. a. What blood type (or types) can be found in an offspring if a mother has type A blood and the father has type B blood? b. What blood type (or types) can be found in an offspring if a mother has type AB blood and the father has type B blood? c. What blood type (or types) can be found in an offspring if a mother has type O blood and the father hastype B blooď?arrow_forwardMatch the genetic disorder to the descriptions below: Edward Syndrome Jacob Syndrome Patau Syndrome Turner Syndrome Prader-Willi Syndrome Down Syndrome (trisomy) Klinefelter Syndrome Cri du Chat 18-Q Deletion Syndrome Translocation Down Syndrome ________ deletion of part of the P arm of chromosome 5. Improperly developed larynx causes cat-like cry until age 2. IQ is under 20. ________ deletion of Q arm of chromosome 15. Affected individuals have a small head, are retarded, and exhibit bizarre behavior. ________ deletion of Q arm of chromosome 18. Affected individuals have thirteen pairs of ribs (normal is 12 pairs) and IQ under 30. ________ extra 21st chromosome attaches to chromosome 14. Affected individ- uals exhibit epicanthic folds of eyelids, simian crease in palms, and retardation. ________ trisomy 18. Affected individuals…arrow_forwardPlease find an Image/Graphic to represent sickle cell disease: Use at least two different images to help the audience understand the cause and/or inheritance pattern of the disorder you chose. Include a brief 1-2 sentence caption below each image that gives a description of the image and explains its relevance to your chosen disorder. The two images should NOT convey the same exact information. Ideas of images to use include: karyotypes, pedigrees, DNA sequences, etc. Please note: the images should be specific to your chosen disorder. The 2 required images must be related to cause and/or inheritance pattern. Images of an individual with the disorder will not count toward your 2 required images as they do not contribute to the audience's understanding of cause and/or inheritance pattern.arrow_forward
- Match the following terms with their correct definitions. A change in a gene that causes it to produce no protein. A loss-of-funtion in one allele that is uominant because the wild type allele alone does not produce enough protein to serve its typical role. 1. Loss-of-function mutation 2. Null mutation 3. Gain-of-function mutation A change in a gene that causes it to produce less protein or protein that is not able to serve its typical role. 4. Haploinsufficiency A change in a gene that causes it to produce increased protein or protein that takes on a new role.arrow_forwardEdio | Calendar X Edio | Student Da x days/1089977/lessons/1533969/variants/2439102/take/10/ A Q TEXT ANSWER The inheritance patterns for some traits in guinea pigs are listed in the table below. 1. Identify the phenotype of a guinea pig with the genotype HhBBrr. 2. Using the allele symbols in the table, identify the genotype of a guinea pig that is recessive for hair length, heterozygous for hair color, and homozygous dominant for hair texture. Trait Dominant Allele Recessive Allele hair short (H) long (h) length hair color black (B) white (b) rough (R) smooth (r) hair texture BIUG X₁ X¹ EEAA H Normal : √x Enter your answer here ŏooooo Questions Answered 中山川 Ω Ο Τ Edio | Calendar X RepostExchange X Practice All Changes Saved Continuearrow_forwardPlease write your complete solution (paper). Albinism in humans is inherited as a simple recessive trait. Determine the genotypes of the parents and their children when two normal parents have 3 normal children and 1 albino.arrow_forward
- Use the given terms (in parentheses) to complete the following sentences. (closed square, controlled mating, diamond, hexagon, open circle, open square, pedigree, two horizontal bars) Due to the limitations of studying humans investigations rely on pedigree analysis. The symbol used in a pedigree for an affected male is a closed square. The symbol for an unaffected female is an open circle. An individual of indeterminate sex is represented by a diamond in a pedigree. In a pedigree a consanguineous mating is diagrammed as_______between a male and a female.arrow_forwardPedigree Analysis Examine the following pedigrees. 1 Examine the pedigree of achondroplasia (a form of dwarfism). a Is this trait dominant or recessive? b How do you know? c Label all of the genotypes on the pedigree chart. II Laboratory Exercise 9 Trait Genetics 113 %3Darrow_forwardC:/Users/korea/Downloads/RNA%20in%20cancer.pdf 田 Edge as your default browser? Set as default Genetics 2 Final Exam Word Insert Design Layout References Mailings Review View Help O Tell me what you want to do (B 10 , 嘴A:ニ.=-元, A A Aa- * 倍 AaBbCcD AaBbCcDe AaBbC AaBbCcDc A a Normal U - abs X2 x A-型,A.A@ - No Spac. Heading 1 Heading 2 Font Paragraph Styles primarily on just seven or eight nucleotides at the 5' end of the miRNA (ca the 'seed region').. Q3: what actually happened if Splicing factor mutated? Give an example and describes the outcome. W 5 words LEEnglish (United States) CHIMZ PolylA) site terized, with implications for tumorigenesis. mRNA export factors generally facilitate use of distal cleav- age and polyadenylation sites, leading to long 3' UTR isoform expression. This requires both the ATY SUO (-3 CSTF2 CHOCI DET receptor NXF1 and cleavage factor Im complex 68 kDa subunit (CFIM68), which cooperate to facilitate nuclear export LUZP4 TREX Cleavage stimulation factor EM prt…arrow_forward
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