Essentials of Genetics
9th Edition
ISBN: 9781292108933
Author: KLUG
Publisher: PEARSON
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Chapter CHST6, Problem 5RQ
Explain how viral vectors can be used for gene therapy and provide two examples of commonly used viral vectors. What are some of the major challenges that must be overcome to develop safer and more effective viral vectors for gene therapy?
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Explain how viral vectors can be used for gene therapy, and provide two examples of commonly used viral vectors. What are some of the major challenges that must be overcome to develop safer and more effective viral vectors for gene therapy?
What are the considerations for choice of a vector in gene therapy?
What is vector? Discuss 2 vectors that are commonly used in DNA recombinant technology.
Chapter CHST6 Solutions
Essentials of Genetics
Ch. CHST6 - What is gene therapy?Ch. CHST6 - Prob. 2RQCh. CHST6 - Prob. 3RQCh. CHST6 - Prob. 4RQCh. CHST6 - Explain how viral vectors can be used for gene...Ch. CHST6 - Prob. 6RQCh. CHST6 - Explain an example of successful gene therapy...Ch. CHST6 - Prob. 8RQCh. CHST6 - Prob. 9RQCh. CHST6 - Describe two gene-silencing techniques and explain...
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- List the three features of a cloning vector and why these elements are neededarrow_forwardWhat are the essential elements of a plasmid cloning vector? Discuss the importance of each element for dna cloning.arrow_forwardWhat is a cloning vector? Give two examples of specific DNA molecules routinely used as cloning vectors.arrow_forward
- Compare and discuss the key features of plasmids that are respectively used as bacterial cloning and bacterial expression vectors.arrow_forwardWhat are the major components of the CRISPR-Cas9 system? What mechanism does it employ to combine DNA? Explain the process of how the CRISP-Cas9 system is able to create recombinant DNA. Relate the idea of gene modification to the fields of vaccines and applied microbiology as well.arrow_forwardPLease explain What characteristics of plasmids makes them good cloning vectors? Discussarrow_forward
- List the advantages and disadvantages of using plasmids as cloning vectors. What advantages do BACs and YACs provide over plasmids as cloning vectors?arrow_forwardWill genome editing emerge as the safest and most reliablemethod of gene therapy, rendering other approachesobsolete, or will a combination of approaches (vectorand nonvector delivery, RNA-based therapeutics, andgenome editing) be necessary depending on the geneticcondition being treated?arrow_forwardExplain How Single-nucleotide mutations can be introduced into the genome using an engineered CRISPR-Cas9 system.arrow_forward
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