Genetic Analysis: An Integrated Approach Plus Mastering Genetics with Pearson eText -- Access Card Package (3rd Edition) (What's New in Genetics)
3rd Edition
ISBN: 9780134807799
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter E, Problem 13P
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Disease name: Chronic myelogenous leukemia (CML)
1. Outline the processes of the best DNA technology tools/techniques involved in the diagnosis of the disease
2. Present the best therapeutic DNA technology tool/technique for the disease by describing the tool and discussing the procedure
3. Identify the challenges or issues that a scientist may face for using the DNA technology diagnostic and therapeutic tools and application
Manufacturers of self-contained test kits apply for and receive Food and Drug Administration (FDA) approval for their particular test to be on the Clinical Laboratory Improvement Amendment (CLIA) waived list. To find out if your particular brand of self-contained test kit is on the CLIA waived list, access an up-to-date listing at the FDA website(https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfclia/analyteswaived.cfm (Links to an external site.)) and use the key search term “Currently Waived Analytes” (be forewarned, though, that the list is very long) (Cited from Chap. 37).
Research the link to the FDA to find your kit name on the list.
Discuss the following questions:
Why would it be important to have this kit listed here?
Can a POL use kits that are not listed?
DGM-StudentWS-CL (2).pdf
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Central Dogma and Genetic Medicine
Click & Learn
Student Worksheet
OVERVIEW
This worksheet complements the Central Dogma and Genetic Medicine Click & Learn.
PROCEDURE
As you proceed through the Click & Learn, follow the instructions below and answer the questions in the spaces
provided.
1. Let's review! The central dogma of molecular biology refers to the process of gene expression, Write the
definition of gene expression in your own words.
2. Click on the "Central Dogma" menu tab at the top of the screen.
The table below outlines the steps in eukaryotic gene expression. Click on each tab or scroll through the page
and briefly summarize each step below.
Gene
Molecules Involved
Summary
Expression
What molecules and proteins
are involved in this step?
What happens during this step?
Steps
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Chapter E Solutions
Genetic Analysis: An Integrated Approach Plus Mastering Genetics with Pearson eText -- Access Card Package (3rd Edition) (What's New in Genetics)
Ch. E - E.1 What is CODIS? Describe the four most...Ch. E - Compare and constast the terms paternity index...Ch. E - What is exclusion principle? How is it used in...Ch. E - What is the statistical principle underlying...Ch. E - Explain the meaning of identity by descent in the...Ch. E - Prob. 6PCh. E - E.7 The results shown are from a DNA test for four...Ch. E - E.8 Figure illustrates the results of an...Ch. E - E.9 Additional STR allele frequency information...Ch. E - Prob. 10P
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