Genetic Analysis: An Integrated Approach Plus Mastering Genetics with Pearson eText -- Access Card Package (3rd Edition) (What's New in Genetics)
3rd Edition
ISBN: 9780134807799
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter E, Problem 5P
Explain the meaning of “identity by descent” in the context of identifying genealogical relationship between individuals. In these analyses, why are segments of chromosomes (haplotypes) rather than individual STRs used to identify genetic relationships?
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Chapter E Solutions
Genetic Analysis: An Integrated Approach Plus Mastering Genetics with Pearson eText -- Access Card Package (3rd Edition) (What's New in Genetics)
Ch. E - E.1 What is CODIS? Describe the four most...Ch. E - Compare and constast the terms paternity index...Ch. E - What is exclusion principle? How is it used in...Ch. E - What is the statistical principle underlying...Ch. E - Explain the meaning of identity by descent in the...Ch. E - Prob. 6PCh. E - E.7 The results shown are from a DNA test for four...Ch. E - E.8 Figure illustrates the results of an...Ch. E - E.9 Additional STR allele frequency information...Ch. E - Prob. 10P
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- Chromosomal rearrangements are a source for reproductive barriers (low hybrid fitness) and are suppressors of recombination. The most commonly referred to rearrangements involved in human evolution are the formation of the Y chromosome and the variation of karyotypes between primates, especially the formation of human chromosome 2. Using the diagram below identify the types of chromosomal rearrangements and describe the impact on genotype.arrow_forwardDuring the resolution of polyploidy, the subgenomes must function as a single unit. This often results in at least partial dominance of one subgenome over the other. Sequencing of polyploid genomes has demonstrated that TE density is often negatively associated with dominance. If you were presented with data suggesting that a subgenome with higher TE density associated with gene space was dominant, how could you explain the results? Describe al follow up experiment.arrow_forwardDescribe the difference between a homozygous and heterozygousgenotype, and represent each symbolically with an example.arrow_forward
- Explain how databases that catalog sequence variationin many people can facilitate the diagnosis of geneticdiseases.arrow_forwardThe diagram below represents results of agarose gel electrophoresis performed after PCR amplification of a molecular marker in diploid organisms. Answer the following questions: a) How many individuals are homozygous and how many are heterozygous? b) How many alleles are there in this population?arrow_forwardDoes a molecular marker have to be polymorphic to be useful in physical mapping studies? Does a molecular marker have to be polymorphic to be useful in linkage mapping (i.e., involving family pedigree studies or genetic crosses)? Explain why or why not.arrow_forward
- Explain at the biochemical or enzymatic level, the phenotypic consequencesof alleles incase of following cross. Rr (pink flower) x Rr (pink flower) (progeny are 1 RR (red flower) :2 Rr (pink flower): 1rr(white flower) how alleles contribute to a phenotype through metabolism.arrow_forwardDescribe five different scenarios where a change in DNA sequence would result in a phenotypic change at the organismal (human) level.arrow_forwardList and explain the five (5) mode of inheritance in pedigree analysis.arrow_forward
- Geneticists study mitochondrial and Y-chromosome DNA to determine the ancestry of modern humans. Such studies have led to the emergence of mitochondrial Eve and Y-chromosome Adam, whose features above are a far-cry from an artist's interpretation of the Biblical narrative. Their progeny came to have the range of physical features now described as racial differences. How has modern genomics contributed to the debate about the validity and definition of these hypothetical parents and their descendants? References:arrow_forwardDefine the terms allele, chromosome, and gene and explain how they relate to one another. Develop an analogy between these terms and the process of using a street map to locate a new apartment to live in next year (i.e., consider which term is analogous to a street, which to a type of building, and which to an apartment floor plan).arrow_forwardDiscuss the principles of the chromosome theory of inheritance. Whichprinciples do you think were deduced via light microscopy, and whichwere deduced from crosses? What modern techniques could be used tosupport the chromosome theory of inheritance?arrow_forward
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