Prostate-specific antigen

The first test is the Conventional Serological Test, which analyses proteins, antigens and enzymes present in blood samples. The elements tested under the Conventional Serological Test are exposed to degradation and requires large samples to obtain best results. The second test is the Restriction Fragment Length Polymorphism, which

In the early stages, symptoms indicating that prostate cancer may have developed are rarely seen, but there are some clinical signs and symptoms that can help determine the presence of this cancer. A neoplasm is a new and abnormal growth of tissue in some part of the body. “If the neoplasm is large enough to encroach on the bladder neck, signs and symptoms of urinary obstruction occur (difficulty and frequency of urination, urinary retention, and decreased size and force of the urinary stream)”

Prostate Cancer The history of prostate cancer is basically a progression of disease from an asymptomatic to symptomatic for patients who have biochemical failure non metastatic disease to metastatic disease and castration sensitive to resist. Over the year, rapid development of number of new drugs that are now FDA approved. More the recent studies of chemo-naïve mCRPC or pre-docetaxel metastatic states, conducted in last 5 years. Early experienced with next generation AR-targeting agent quickly

Introduction Prostate cancer (PC) has surpassed lung cancer as the most commonly diagnosed cancer in men. An estimated 230,000 new cases were diagnosed in 2014, accounting for 27% of new cancer cases in men [1]. Although 80–90% of PC with metastatic lesions responds to initial androgen ablation therapy, most of these patients ultimately develop progressive disease of hormone refractory cancer [2]. Obesity, as a growing epidemic all over the world, has been linked to mortality of several cancers [3]

Sicsic Fall 2014 Carcinoma of the prostate, commonly known as prostate cancer, is a diagnosis of a "malignant tumor (adenocarcinoma) of the prostate gland" (Chabner). The prostate is a significant muscular organ that belongs to the male reproductive system. Approximately the size of a walnut, the prostate is "located at the base of the bladder and in front of the rectum" (Prostate Gland). In conjunction to the seminal vesicles and the Cowper 's glands, the prostate secretes fluids that contain "sperm

down-regulation of Acute Phase Response Signaling and LXR/RXR activation pathways in prostate cancer Abstract: Detecting prostate cancer (PCa) using non-invasive diagnostic markers still remains a challenge. The aim of this study was the identification of urine proteins sufficiently sensitive and specific to detect PCa in the early stages. Comparative proteomics profiling of urine from patients with PCa, benign prostate hyperplasia, bladder cancer and renal cancer, coupled with bioinformatics analysis

The records have been reviewed. The member is an adult male with a birth date of 03/10/1960. He has a diagnosis of prostate cancer. His treating provider, Samuel Torres, MD, recommended the Oncotype DX Prostate Cancer Assay, which was performed on 12/30/2015. The carrier has denied coverage of Oncotype DX Prostate Cancer Assay as experimental and/or investigational and not medically necessary. A letter from the carrier to the provider, dated 06/22/2016, states in part: “Claim number 201602083184074

Introduction The prostate is a small gland that encloses the urethra directly below the bladder. This organ consists of approximately twenty to thirty compound tuvuloalveolar glands found within smooth muscle and dense connective tissue. During sexual activity, more specifically ejaculation, the prostate contracts and releases a fluid that plays a crucial role in activating males’ sperm, producing semen. The prostate is also important because it houses citrate, a source of nutrients for one’s body

Cancer is a group of over 100 diseases involving uncontrolled growth of abnormal cells in the body with very high potential to spread to other body parts. Untreated cancers can cause serious illness and may lead to the death of the individual. In humans, over two hundred different forms of cancers have been identified, affecting more than sixty organs and claiming millions of lives worldwide.1 In the modern era, cancer is one of the major public health problems worldwide. Based on the GOBOCAN report

History In 2013 there were 238,500 new cases of Prostate Cancer diagnosed in the United Sates, and about 29,700 of the cases will die from it according to WebMD.com. Prostate Cancer is the most non-skin related cancer in the United States. Prostate cancer is the formation of cancerous cells in the prostate of the male’s reproductive organ. Prostate cancer is a slow progressing disease, and most men only die once they have reached old age. Because the prostate is in close proximity to other organs, it also