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2. A reversion is a mutation that returns a mutant codon back to a codon that gives a wild-type phenotype. At the DNA level, this type of mutation can be an exact reversion or an equivalent reversion. GAG First GTG Exact GAG (glutamic acid) mutation (valine) reversion (glutamic acid) GAG - GTG First Equivalent (valine) reversion GAA (glutamic acid) mutation (glutamic acid) GAG First GTG Equivalent - GAT (glutamic acid) mutation (valine) reversion (aspartic acid) An equivalent reversion produces a protein that is equivalent to the wild type in structure and function. This can occur in two ways. In some cases, the reversion produces the wild-type amino acid (in this case, glutamic acid), but it uses a different codon than the wild-type gene. Alternatively. an equivalent reversion may substitute an amino acid structurally similar to the wild-type amino acid. In our example, an equivalent reversion has changed valine to an aspartic acid. Because aspartic and glutamic acids are structurally similar-they are acidic amino acids-this type of reversion can restore wild-type structure and function. Now here is the question. The template strand within the coding sequence of a gene has the following sequence: 3'-TACCCCTTCGACCCCGGA-5' This template produces the following mRNA: 5'-AUGGGGAAGCUGGGGCCA–3' The MRNA encodes a polypeptide with the following sequence: methionine-glycine-lysine–leucine-glycine-proline. A mutation changes the template strand to this sequence: 3'-TACCCCTACGACCCCGGA-5' After the first mutation, another mutation occurs to change this sequence again. Is each of the following second mutations an exact reversion, an equivalent reversion, or neither? 3'-TACCCCTCCGACCCCGGA-5' 3'-TACCCCTTCGACCCCGGA-5' 3'-TACCCCGACGACCCCGGA-5'

2. A reversion is a mutation that returns a mutant codon back to a codon that gives a wild-type phenotype. At the DNA level, this type of mutation can be an exact reversion or an equivalent reversion. GAG First GTG Exact GAG (glutamic acid) mutation (valine) reversion (glutamic acid) GAG - GTG First Equivalent (valine) reversion GAA (glutamic acid) mutation (glutamic acid) GAG First GTG Equivalent - GAT (glutamic acid) mutation (valine) reversion (aspartic acid) An equivalent reversion produces a protein that is equivalent to the wild type in structure and function. This can occur in two ways. In some cases, the reversion produces the wild-type amino acid (in this case, glutamic acid), but it uses a different codon than the wild-type gene. Alternatively. an equivalent reversion may substitute an amino acid structurally similar to the wild-type amino acid. In our example, an equivalent reversion has changed valine to an aspartic acid. Because aspartic and glutamic acids are structurally similar-they are acidic amino acids-this type of reversion can restore wild-type structure and function. Now here is the question. The template strand within the coding sequence of a gene has the following sequence: 3'-TACCCCTTCGACCCCGGA-5' This template produces the following mRNA: 5'-AUGGGGAAGCUGGGGCCA–3' The MRNA encodes a polypeptide with the following sequence: methionine-glycine-lysine–leucine-glycine-proline. A mutation changes the template strand to this sequence: 3'-TACCCCTACGACCCCGGA-5' After the first mutation, another mutation occurs to change this sequence again. Is each of the following second mutations an exact reversion, an equivalent reversion, or neither? 3'-TACCCCTCCGACCCCGGA-5' 3'-TACCCCTTCGACCCCGGA-5' 3'-TACCCCGACGACCCCGGA-5'

Biology: The Dynamic Science (MindTap Course List)
Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Chapter15: From Dna To Protein
Section: Chapter Questions
Problem 5TYK: Which of the following statements is false? a. GTP is an energy source during various stages of...
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2. A reversion is a mutation that returns a mutant codon back to a codon that gives a wild-type phenotype. At the DNA level, this type of mutation can be an exact reversion or an equivalent reversion. GAG First GTG Exact GAG (glutamic acid) mutation (valine) reversion (glutamic acid) GAG - GTG First Equivalent (valine) reversion GAA (glutamic acid) mutation (glutamic acid) GAG First GTG Equivalent - GAT (glutamic acid) mutation (valine) reversion (aspartic acid) An equivalent reversion produces a protein that is equivalent to the wild type in structure and function. This can occur in two ways. In some cases, the reversion produces the wild-type amino acid (in this case, glutamic acid), but it uses a different codon than the wild-type gene. Alternatively. an equivalent reversion may substitute an amino acid structurally similar to the wild-type amino acid. In our example, an equivalent reversion has changed valine to an aspartic acid. Because aspartic and glutamic acids are structurally similar-they are acidic amino acids-this type of reversion can restore wild-type structure and function. Now here is the question. The template strand within the coding sequence of a gene has the following sequence: 3'-TACCCCTTCGACCCCGGA-5' This template produces the following mRNA: 5'-AUGGGGAAGCUGGGGCCA–3' The MRNA encodes a polypeptide with the following sequence: methionine-glycine-lysine–leucine-glycine-proline. A mutation changes the template strand to this sequence: 3'-TACCCCTACGACCCCGGA-5'
Transcribed Image Text:2. A reversion is a mutation that returns a mutant codon back to a codon that gives a wild-type phenotype. At the DNA level, this type of mutation can be an exact reversion or an equivalent reversion. GAG First GTG Exact GAG (glutamic acid) mutation (valine) reversion (glutamic acid) GAG - GTG First Equivalent (valine) reversion GAA (glutamic acid) mutation (glutamic acid) GAG First GTG Equivalent - GAT (glutamic acid) mutation (valine) reversion (aspartic acid) An equivalent reversion produces a protein that is equivalent to the wild type in structure and function. This can occur in two ways. In some cases, the reversion produces the wild-type amino acid (in this case, glutamic acid), but it uses a different codon than the wild-type gene. Alternatively. an equivalent reversion may substitute an amino acid structurally similar to the wild-type amino acid. In our example, an equivalent reversion has changed valine to an aspartic acid. Because aspartic and glutamic acids are structurally similar-they are acidic amino acids-this type of reversion can restore wild-type structure and function. Now here is the question. The template strand within the coding sequence of a gene has the following sequence: 3'-TACCCCTTCGACCCCGGA-5' This template produces the following mRNA: 5'-AUGGGGAAGCUGGGGCCA–3' The MRNA encodes a polypeptide with the following sequence: methionine-glycine-lysine–leucine-glycine-proline. A mutation changes the template strand to this sequence: 3'-TACCCCTACGACCCCGGA-5'
After the first mutation, another mutation occurs to change this sequence again. Is each of the following second mutations an exact reversion, an equivalent reversion, or neither? 3'-TACCCCTCCGACCCCGGA-5' 3'-TACCCCTTCGACCCCGGA-5' 3'-TACCCCGACGACCCCGGA-5'
Transcribed Image Text:After the first mutation, another mutation occurs to change this sequence again. Is each of the following second mutations an exact reversion, an equivalent reversion, or neither? 3'-TACCCCTCCGACCCCGGA-5' 3'-TACCCCTTCGACCCCGGA-5' 3'-TACCCCGACGACCCCGGA-5'
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