24. Use the table below to answer the following question. The template strand of a gene contains this sequence: 3'-TAC TAG GCT AGT TGA-5'. A mutation occurs due to exposure to a chemical mutagen that changes the gene sequence to 3'-TAC TAG ACT AGT TGA-5'. How does this mutation affect the resulting amino acid sequence? (LS3-2) * Second mRNA base UAU Tyr UAC UCU UGU UUU Phe UUC U Cys UCC Ser UCA UGC Gly (G) Phe Leu (F) (L) Glu UUA Leu UUG UAA Stop UGA Stop Ser Asp (E) (D) (S) Tyr (Y) UCG UAG Stop UGG Trp GU A G U Ala (A) CUU CCU CAU CGU U A His CUC G CC Pro ССА CAC CGC Arg CGA Cys (C) Leu Val CUA CAA Gln CAG (V) GTrp (W) CUG CCG CGG Arg (R) G A C Leu AUU ACU AAU AGU (L) Asn A C Ser Ser (S) AUC Ile ACC AAC AGC Thr ACA A CUG Lys (K) AUA Pro AAA Lys AAG AGA Arg AGG Asm (P) AUG Met or start ACG (N) Thr (T) His (H) Gln GUU GCU GAU Asp GAÇ GGU (Q) lle Arg (R) (U) GUC Val GUA GCC Ala GCA GGC Gly GGA GAA Glu GAG GUG GCG GGG O The mutation changes a single amino acid to another amino acid. O The mutation does not affect the amino acid sequence. O The mutation eliminates the stop codon in the third triplet. The mutation introduces a stop codon. First mRNA base (5' end of codon) Third mRNA base (3' end of codon)

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter30: Protein Synthesis
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Problem 1P
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AGUC
24. Use the table below to answer the following question. The template
strand of a gene contains this sequence: 3'-TAC TAG GCT AGT TGA-5'. A
mutation occurs due to exposure to a chemical mutagen that changes the
gene sequence to 3'-TAC TAG ACT AGT TGA-5'. How does this mutation
affect the resulting amino acid sequence? (LS3-2) *
Second mRNA base
A
UCU
UGU
Cys
UGC
UUU
UAU
Tyr
UAC
Phe
UUC
U
UCC
Ser
UCA
Phe
Gly
(G)
Leu
Glu
(F)
(L)
UUA
UAA Stop UGA Stop A
Ser
Asp (E)
(D)
Leu
(S)
UCG
UUG
UAG Stop UGG Trp
Tyr
(Y)
Ala
CUU
CCU
CAU
CGU
U
(A)
His
C
G U
A
CỤC
Leu
CUA
CC
Pro
CCA
CAC
CGC
Arg
CGA
Cys (C)
G
A
Val
CAA
(V)
Gln
G Trp (W)
CUG
CCG
CAG
CGG
G
Arg (R)
G
А С
A
Leu
AUU
ACU
AAU
AGU
(L)
Asn
Ser
Ser (S)
AUC Ile
ACC
Thr
ACA
AAC
AGC
C/
Lys (K)
UGA
AUA
Pro
AAA
Lys
AAG
AGA
Arg
AGG
Asn
(N)
(P)
AUG Met or
start
ACG
His
Thr
(T)
Gin (H)
(Q)
GUU
GCU
GAU
GGU
lle
Asp
Arg
(R)
(1)
GUC
Val
GUA
GCC
GAC
GGC
Ala
GCA
Gly
GGA
GAA
Glu
GAG
GUG
GCG
GGG
The mutation changes a single amino acid to another amino acid.
The mutation does not affect the amino acid sequence.
The mutation eliminates the stop codon in the third triplet.
O The mutation introduces a stop codon.
First mRNA base (5' end of codon)
Third mRNA base (3' end of codon)
Transcribed Image Text:AGUC 24. Use the table below to answer the following question. The template strand of a gene contains this sequence: 3'-TAC TAG GCT AGT TGA-5'. A mutation occurs due to exposure to a chemical mutagen that changes the gene sequence to 3'-TAC TAG ACT AGT TGA-5'. How does this mutation affect the resulting amino acid sequence? (LS3-2) * Second mRNA base A UCU UGU Cys UGC UUU UAU Tyr UAC Phe UUC U UCC Ser UCA Phe Gly (G) Leu Glu (F) (L) UUA UAA Stop UGA Stop A Ser Asp (E) (D) Leu (S) UCG UUG UAG Stop UGG Trp Tyr (Y) Ala CUU CCU CAU CGU U (A) His C G U A CỤC Leu CUA CC Pro CCA CAC CGC Arg CGA Cys (C) G A Val CAA (V) Gln G Trp (W) CUG CCG CAG CGG G Arg (R) G А С A Leu AUU ACU AAU AGU (L) Asn Ser Ser (S) AUC Ile ACC Thr ACA AAC AGC C/ Lys (K) UGA AUA Pro AAA Lys AAG AGA Arg AGG Asn (N) (P) AUG Met or start ACG His Thr (T) Gin (H) (Q) GUU GCU GAU GGU lle Asp Arg (R) (1) GUC Val GUA GCC GAC GGC Ala GCA Gly GGA GAA Glu GAG GUG GCG GGG The mutation changes a single amino acid to another amino acid. The mutation does not affect the amino acid sequence. The mutation eliminates the stop codon in the third triplet. O The mutation introduces a stop codon. First mRNA base (5' end of codon) Third mRNA base (3' end of codon)
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