8. Another unique feature of coronaviruses is usage of a -1 ribosomal frameshift. Explain this frameshift and its significance for the expression of all 16 Nsp proteins, and what two signals drive the -1 ribosomal frameshift?

8. Another unique feature of coronaviruses is usage of a -1 ribosomal frameshift. Explain this frameshift and its significance for the expression of all 16 Nsp proteins, and what two signals drive the -1 ribosomal frameshift?

Biology 2e

2nd Edition

ISBN:9781947172517

Author:Matthew Douglas, Jung Choi, Mary Ann Clark

Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark

Chapter21: Viruses

Section: Chapter Questions

Problem 26CTQ: One of the first and most important targets for drugs to fight infection with HIV (a retrovirus) is...

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Concept explainers

Viral Infections

Viruses are abundantly found, minute entities that have genetic material enclosed within a protein coat. The proteinaceous material enclosing the genetic material of the virus is called a capsid. The genetic material could be either DNA (deoxyribonucleic acid) or RNA (ribonucleic acid). A virus is too minute to be looked at with naked eyes and therefore visualized with the help of a microscope. They are acellular entities that require a host for processes, such as replication, transcription, translation and multiplication. Plants, animals, and bacteria act as host wherein the virus reproduce. Viruses cannot multiply outside the host's body and thus are considered nonliving outside the host body.

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8. Another unique feature of coronaviruses is usage of a -1 ribosomal frameshift. Explain this frameshift and its
significance for the expression of all 16 Nsp proteins, and what two signals drive the -1 ribosomal frameshift?

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