(i)Describe the mechanism of chymotrypsin in cleaving a peptide bond, highlighting theroles of the catalytice triad for the two phases of the catalytic reactions. Explain thesignificance of the oxyanion hole for the catalysis.(ii)All serine proteases contain the catalytic triad and these amino acids are positioned inthe exact same conformation. Since this is true, why do trypsin and chymotrypsinhave such different substrate specificity? What features of the enzyme allow for thissituation?

Answer i- A catalytic triad is a group of three amino acids present in the active site of some…

Answered: Describe the mechanism of chymotrypsin…

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter25: Nitrogen Acquisition And Amino Acid Metabolism

Section: Chapter Questions

Problem 19P

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