Below are shown two views of the backbone representation of the Myc-Max complex binding to DNA (PDB ID: 1NPK). Myc and Max are members of the basic helix-loop-helix (BHLH) class of DNA- binding proteins (see Chapter 29). Myc (red) and Max (blue) associ- ate via a coiled-coil interaction and bind DNA as a dimer. Side view of Myc-Max bound to DNA Top view of Myc-Max bound to DNA (looking down the DNA helical axis) (a) Are the helices bound to the DNA likely to be amphiphilic? Explain. (b) Where do you predict the N- and C-termini are located for Max?
Below are shown two views of the backbone representation of the Myc-Max complex binding to DNA (PDB ID: 1NPK). Myc and Max are members of the basic helix-loop-helix (BHLH) class of DNA- binding proteins (see Chapter 29). Myc (red) and Max (blue) associ- ate via a coiled-coil interaction and bind DNA as a dimer. Side view of Myc-Max bound to DNA Top view of Myc-Max bound to DNA (looking down the DNA helical axis) (a) Are the helices bound to the DNA likely to be amphiphilic? Explain. (b) Where do you predict the N- and C-termini are located for Max?
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter9: Gene Expression And Gene Regulation
Section: Chapter Questions
Problem 16QP: Given the following tRNA anticodon sequence, derive the mRNA and the DNA template strand. Also,...
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