Experiment I: Scientists took two types of human epithelial cells and placed them in an experimental system that could measure intracellular (IN) and extracellular concentration (OUT) of 3 substances: Na+, ATP and Glucose. Cell type A was nonmutant whereas cell type B had a mutation in a transmembrane protein. At the beginning, middle and end of the experiment, concentrations were measured for all three substances as shown below. Cell type A (non-mutant) Time IN [Na+] 0 10 ms 20 ms Concentration in mM 200- 150 150mM 25mM 150mM 100 Q1. Analyze the intracellular concentration changes in the table (above) and the graph (below left). Label the key at the bottom left. Graph the extracellular concentration changes in this data set using the graph below right and the same key. With cell image on bottom right, diagram what is happening using arrows and labels for the transported substance. And finally, at the bottom of the page describe what is happening using words i.e. powers the movement of in/out of the cell. Intracellular concentrations Extracellular concentrations 50 0 OUT [Na+] 15mM 140mM 15mM KEY 10 IN [ATP] 200mM 70mM 70mM Time in milliseconds 20 Concentration in mM 200 150 100 IN [Glu] 5mM 5mM 135mM 50 OUT [Glu] 200mM 200mM 55mM 0 10 Time in milliseconds 20
Experiment I: Scientists took two types of human epithelial cells and placed them in an experimental system that could measure intracellular (IN) and extracellular concentration (OUT) of 3 substances: Na+, ATP and Glucose. Cell type A was nonmutant whereas cell type B had a mutation in a transmembrane protein. At the beginning, middle and end of the experiment, concentrations were measured for all three substances as shown below. Cell type A (non-mutant) Time IN [Na+] 0 10 ms 20 ms Concentration in mM 200- 150 150mM 25mM 150mM 100 Q1. Analyze the intracellular concentration changes in the table (above) and the graph (below left). Label the key at the bottom left. Graph the extracellular concentration changes in this data set using the graph below right and the same key. With cell image on bottom right, diagram what is happening using arrows and labels for the transported substance. And finally, at the bottom of the page describe what is happening using words i.e. powers the movement of in/out of the cell. Intracellular concentrations Extracellular concentrations 50 0 OUT [Na+] 15mM 140mM 15mM KEY 10 IN [ATP] 200mM 70mM 70mM Time in milliseconds 20 Concentration in mM 200 150 100 IN [Glu] 5mM 5mM 135mM 50 OUT [Glu] 200mM 200mM 55mM 0 10 Time in milliseconds 20
Biology 2e
2nd Edition
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark
Chapter5: Structure And Function Of Plasma Membranes
Section: Chapter Questions
Problem 7RQ: A scientist compares the plasma membrane composition of an animal from the Mediterranean coast with...
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