Give 1 example of diseases arising from each of the following mutations and explain each. Point mutation Frameshift mutation

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter11: Genome Alterations: Mutation And Epigenetics
Section: Chapter Questions
Problem 9QP: Define and compare the following types of nucleotide substitutions. Which is likely to cause the...
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  1. Give 1 example of diseases arising from each of the following mutations and explain each.
    1. Point mutation
    2. Frameshift mutation
  2. Calculate for the DNA concentration. The absorbance at 260 nm is 0.7 at 1:30 dilution; the absorbance at 320 nm is 0.1. 
  3. Is the DNA isolated of good quality? The absorbance at 260 nm is 0.7; the absorbance at 280 nm is 0.1; the absorbance at 320 is 0.01. 
  4. If you do an absorbance reading after plasmid purification and get an A260/A280 of less than 1.8, how could you further purify the sample to get rid of the protein contamination? Is it always necessary to have completely pure DNA? What are some cases where it would or would not be?
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