intramolecular intermolecular 1. Propose an experiment involving a singly-labelled substrate that could distinguish between these possibilities. Consider the symmetry of the resonance stabilised cationic fragment in the intermolecular pathway.

Chemistry
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ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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Chapter1: Chemical Foundations
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Problem: Labelling
The rearrangement below could proceed by intramolecular or intermolecular mechanisms.
OH
intramolecular
intermolecular
1. Propose an experiment involving a singly-labelled substrate that could distinguish between these
possibilities. Consider the symmetry of the resonance stabilised cationic fragment in the
intermolecular pathway.
Designing lobelling experiments: check if the hypothetical mechanisms lead to different connectivities in the
product; label one otom that would be bonded to different atoms in the products depending on the mechanism.
Transcribed Image Text:Problem: Labelling The rearrangement below could proceed by intramolecular or intermolecular mechanisms. OH intramolecular intermolecular 1. Propose an experiment involving a singly-labelled substrate that could distinguish between these possibilities. Consider the symmetry of the resonance stabilised cationic fragment in the intermolecular pathway. Designing lobelling experiments: check if the hypothetical mechanisms lead to different connectivities in the product; label one otom that would be bonded to different atoms in the products depending on the mechanism.
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