Make a rough drawing of the four complexes in the Electron Transport Chain. Label each side of the mitochondrial membrane and show the direction and number of protons pumped at each site.
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- Using the answer code on the right, indicate which form of energy production is being described: 1. takes place in the mitochondrial matrix 2. produces H2O as a by-product 3. results in a rich yield of ATP 4. takes place in the cytosol 5. processes acetyl-CoA 6. takes place in the mitochondrial innermembrane cristae 7. converts glucose into two pyruvate molecules 8. uses molecular oxygen 9. accomplished by the electron transport system and ATP synthase (a) glycolysis (b) citric acid cycle (c) oxidative phosphorylationBelow is a diagram of the mitochondrial electron transport chain. Arrows indicate the direction of electron flow between the components of this chain. Identify each lettered item by filling in the blanks below the diagram.Describe the movement of protons that is caused by the action of the mitochondrial electron transport chain and explain why more ATP can be generated from the addition of NADH to the system as opposed to succinate.
- The proton-motive force is a measure of the potential energy generated across the mitochondrial inner membrane during electron transport. Explain the factors that constitute this potential energy, that will be converted to the chemical energy of ATP by the cell. (4)In the section dealing with “NAD+ in disease” it is mentioned that metabolomics results indicate that impaired mitochondrial function contributes to some of the mentioned diseases. Which metabolites can potentially accumulate when complex I of the electron transport chain is defective? Use Fig 1 for guidance.Two mobile electron transfer carriers are present in the inner mitochondrial membrane. Name these two carriers.
- In phase II of ETS diagram and label the ATP synthase along with the inner mitochondrial membrane it is sitting in. Your diagram must show the intermembrane space and the mitochondrial matrix. Describe how it works step by stepUncoupling agents are proteins spanning the inner mitochondrial membrane that allow protons to pass through the membrane and bypass the channel of ATP synthase. Describe the consequences to the proton gradient and ATP production.?In the electron transport chain, electrons are transferred to enzyme complexes. Name the complexes of the ETC, electron donor, and determine the number of H+ ions that are pumped in each complexes
- Describe the involvements of the followings in the electron transport centre in the inner mitochondrial membrane.(a). Rieske center(b). Ubiquinone(c). ProtonsAssume there is no cyanide poisoning. What would happen if the inner mitochondrial membrane was permeabilized to the point where it no longer served as a barrier, affecting the proton gradient and ATP synthesis?Draw a simple word diagram showing the path of electrons through the electron-transport chain.b) On your word diagram below, circle the complexes that pump protons across the inner mitochondrial membrane. Put a box around mobile electron carriers.
