Question:- 4. What product in this metabolic pathway could feedback to inhibit the pathway? What type of inhibition? 6. What is the sign of Delta G in Step "3" and "6"

Biochemistry
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ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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Question:-

4. What product in this metabolic pathway could feedback to inhibit the pathway? What type of

inhibition?

6. What is the sign of Delta G in Step "3" and "6"

H
H
H
H-C=O
H--OH
H-C-OH
CO ATP ADP
ATP ADP H--OH
но-с-н
HO-C-H
**1-KE
H-C-O-P-O
C-06 4a
HOCH Fructose
H-C-OH
H-C-OH
Phosphoglucose
bisphosphate
aldose
Hexokinase
OH H
HO
OH
H-C-OH
Phosphofructo
H-C-OHO kina
Isomerase
H--0--02 H--0--03
H-C-OHO
OH
H-C-OHO-
H-C-O-P-0 4b
6-
H
H
Glucose
Glucose 6-phosphate Fructose 6-phosphate Fructose 1, 6-bisphosphate
5b
GLYCOLYSIS
H₂O
0
H-C=O
H-C-H
H
Pyruvate
ATP ADP 0 0
pyruvate
kinase
0
H-C-O-P-O
6-
HH
Phosphoenolpyruvate
(PEP)
Enolase
8
HO
H-C-O-P-O
Co d
HO-C-H
H
Glyceraldehyde
3-phosphate
dehydrogenase
2X
ATP ADP
0
H-C-O-P-O
H-C-OHO
H
H-OHO phosphaglycerate-C-0-0 phospholycerate
kinase
7
H 6-
6
2-Phosphoglycerate 3-Phosphoglycerate
Dihydroxyacetone
phosphate
Trione
phosphate 5a
isomerase
H
C-0
H-C-OHO
Glyceraldehyde
H-C-O-P-0 3-phosphate
HO
NAD + P
NADH + H*
O-P=O
6
C=0
H-C-OHO
H-C-0-P=O
HO
1,3-Bisphosphoglycerate
Transcribed Image Text:H H H H-C=O H--OH H-C-OH CO ATP ADP ATP ADP H--OH но-с-н HO-C-H **1-KE H-C-O-P-O C-06 4a HOCH Fructose H-C-OH H-C-OH Phosphoglucose bisphosphate aldose Hexokinase OH H HO OH H-C-OH Phosphofructo H-C-OHO kina Isomerase H--0--02 H--0--03 H-C-OHO OH H-C-OHO- H-C-O-P-0 4b 6- H H Glucose Glucose 6-phosphate Fructose 6-phosphate Fructose 1, 6-bisphosphate 5b GLYCOLYSIS H₂O 0 H-C=O H-C-H H Pyruvate ATP ADP 0 0 pyruvate kinase 0 H-C-O-P-O 6- HH Phosphoenolpyruvate (PEP) Enolase 8 HO H-C-O-P-O Co d HO-C-H H Glyceraldehyde 3-phosphate dehydrogenase 2X ATP ADP 0 H-C-O-P-O H-C-OHO H H-OHO phosphaglycerate-C-0-0 phospholycerate kinase 7 H 6- 6 2-Phosphoglycerate 3-Phosphoglycerate Dihydroxyacetone phosphate Trione phosphate 5a isomerase H C-0 H-C-OHO Glyceraldehyde H-C-O-P-0 3-phosphate HO NAD + P NADH + H* O-P=O 6 C=0 H-C-OHO H-C-0-P=O HO 1,3-Bisphosphoglycerate
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