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Suppose Nicole recently learned that she inherited a mutant BRCA1 allele from her mother, who had breast cancer. BRCA1 is a tumor suppressor gene that is related to breast cancer. Why would Nicole be at higher risk for getting breast cancer at an earlier age than her sister, Francine, who inherited a normal BRCA1 allele from their mother? An individual who inherited two functional alleles of a tumor suppressor gene is less likely to eat highly carcinogenic foods. One mutant allele of a tumor suppressor gene increases the likelihood that the wild-type allele will also mutate. A person who inherited two functioning alleles of a tumor suppressor gene needs both alleles to mutate for tumors to develop. If an individual has even one mutation in a tumor suppressor gene, cancer will not be suppressed.

Suppose Nicole recently learned that she inherited a mutant BRCA1 allele from her mother, who had breast cancer. BRCA1 is a tumor suppressor gene that is related to breast cancer. Why would Nicole be at higher risk for getting breast cancer at an earlier age than her sister, Francine, who inherited a normal BRCA1 allele from their mother? An individual who inherited two functional alleles of a tumor suppressor gene is less likely to eat highly carcinogenic foods. One mutant allele of a tumor suppressor gene increases the likelihood that the wild-type allele will also mutate. A person who inherited two functioning alleles of a tumor suppressor gene needs both alleles to mutate for tumors to develop. If an individual has even one mutation in a tumor suppressor gene, cancer will not be suppressed.

Human Heredity: Principles and Issues (MindTap Course List)
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter12: Genes And Cancer
Section: Chapter Questions
Problem 15QP: Which of the following mutations will result in cancer? a. homozygous recessive mutation in a...
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Suppose Nicole recently learned that she inherited a mutant BRCA1 allele from her mother, who had breast cancer. BRCA1 is a tumor suppressor gene that is related to breast cancer. Why would Nicole be at higher risk for getting breast cancer at an earlier age than her sister, Francine, who inherited a normal BRCA1 allele from their mother? An individual who inherited two functional alleles of a tumor suppressor gene is less likely to eat highly carcinogenic foods. One mutant allele of a tumor suppressor gene increases the likelihood that the wild-type allele will also mutate. A person who inherited two functioning alleles of a tumor suppressor gene needs both alleles to mutate for tumors to develop. O If an individual has even one mutation in a tumor suppressor gene, cancer will not be suppressed.
Transcribed Image Text:Suppose Nicole recently learned that she inherited a mutant BRCA1 allele from her mother, who had breast cancer. BRCA1 is a tumor suppressor gene that is related to breast cancer. Why would Nicole be at higher risk for getting breast cancer at an earlier age than her sister, Francine, who inherited a normal BRCA1 allele from their mother? An individual who inherited two functional alleles of a tumor suppressor gene is less likely to eat highly carcinogenic foods. One mutant allele of a tumor suppressor gene increases the likelihood that the wild-type allele will also mutate. A person who inherited two functioning alleles of a tumor suppressor gene needs both alleles to mutate for tumors to develop. O If an individual has even one mutation in a tumor suppressor gene, cancer will not be suppressed.
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