The article “Assessment of Dermopharmacokinetic Approach in the Bioequivalence Determination of Topical Tretinoin Gel Products” (L. Pershing, J. Nelson, et al., J Am Acad Dermatol 2003:740–751) reports that the amount of a certain antifungal ointment that is absorbed into the skin can be modeled with a lognormal distribution. Assume that the amount (in ng/cm²) of active ingredient in the skin two hours after application is lognormally distributed with μ = 2.2 and σ = 2.1. a) Find the mean amount absorbed. b) Find the median amount absorbed. c) Find the probability that the amount absorbed is more than 100 ng/cm². d) Find the probability that the amount absorbed is less than 50 ng/cm². e) Find the 80th percentile of the amount absorbed. f) Find the standard deviation of the amount absorbed.

Glencoe Algebra 1, Student Edition, 9780079039897, 0079039898, 2018
18th Edition
ISBN:9780079039897
Author:Carter
Publisher:Carter
Chapter10: Statistics
Section10.1: Measures Of Center
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The article “Assessment of Dermopharmacokinetic Approach in the Bioequivalence Determination of Topical Tretinoin Gel Products” (L. Pershing, J. Nelson, et al., J Am Acad Dermatol 2003:740–751) reports that the amount of a certain antifungal ointment that is absorbed into the skin can be modeled with a lognormal distribution. Assume that the amount (in ng/cm²) of active ingredient in the skin two hours after application is lognormally distributed with μ = 2.2 and σ = 2.1. a) Find the mean amount absorbed. b) Find the median amount absorbed. c) Find the probability that the amount absorbed is more than 100 ng/cm². d) Find the probability that the amount absorbed is less than 50 ng/cm². e) Find the 80th percentile of the amount absorbed. f) Find the standard deviation of the amount absorbed.

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