Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 1, Problem 5CONQ
Summary Introduction
To review:
Whether the following examples are description of genetics at the molecular, cellular, organism or population level.
A. The HbS allele encodes a polypeptide that functions slightly differently from the polypeptide encoded by the HbA allele.
B. If an individual has two copies of the Hbs allele, that person’s red blood cells take on a sickle shape.
C. Individuals who have two copies of the HbA allele do not have sickle cell disease, but they are not resistant to malaria. People who have one HbA allele and one HbS allele do not have sickle cell disease and are resistant to malaria. People who have two copies of the HbS allele have sickle cell disease and this disease may significantly shorten their lives.
D. Individuals with sickle cell disease have anemia because their red blood cells are destroyed by the body.
Introduction:
The blood disease called sickle cell anemia is a heritable disease. The affected individuals do not have enough oxygen-carrying hemoglobin in their blood, which causes the red blood cells (RBCs) to shrink and acquire a sickle shape. This happens due to the defective β–globin gene.
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Sickle cell anemia is a disease that is caused by a mutation in the gene that produces hemoglobin. Hemoglobin carries oxygen in red blood cells. The HbA allele produces normal hemoglobin and the HbS allele produces hemoglobin that sticks together and causes red blood cells to sickle. Heterozygous individuals (HbAHbS) produce both normal and "sickle" hemoglobin so the HbA and HbS alleles are codominant. Heterozygotes do not develop sickle cell anemia and are described as having the sickle cell trait. Individuals that are homozygous for the sickle allele (HbSHbS) only produce "sickle" hemoglobin and develop sickle cell disease.A man who is homozygous for the normal allele married a woman with the sickle cell trait. What is the expected probability of this couple having a boy with the sickle cell trait? Record your answer as a value between 0 and 1 rounded to two decimal places.Answer
Sickle cell anemia is a disease that is caused by a mutation in the gene that produces hemoglobin. Hemoglobin carries oxygen in red blood cells. The HbA allele produces normal hemoglobin and the HbS allele produces hemoglobin that sticks together and causes red blood cells to sickle. Heterozygous individuals (HbAHbS) produce both normal and "sickle" hemoglobin so the HbA and HbS alleles are codominant. Heterozygotes do not develop sickle cell anemia and are described as having the sickle cell trait. Individuals that are homozygous for the sickle allele (HbSHbS) only produce "sickle" hemoglobin and develop sickle cell disease.
A man with the sickle cell trait married a woman with the sickle cell trait. Determine the probability that they will have children with the sickle cell trait or sickle cell disease.Record your answer as a value between 0 and 1 rounded to two decimal places. Answer
A human gene called the β-globin gene encodes a polypeptidethat functions as a subunit of the protein known as hemoglobin.Hemoglobin is found within red blood cells; it carries oxygen. Inhuman populations, the β-globin gene can be found as the common allele called the HbAallele, and it can also be found as theHbSallele. Individuals who have two copies of the HbSallele havethe disease called sickle cell disease. Are the following examplesdescriptions of genetics at the molecular, cellular, organism, orpopulation level?A. The HbSallele encodes a polypeptide that functions slightlydifferently from the polypeptide encoded by the HbAallele.B. If an individual has two copies of the HbSallele, that person’sred blood cells take on a sickle shape.C. Individuals who have two copies of the HbAallele do nothave sickle cell disease, but they are not resistant to malaria.People who have one HbAallele and one HbSallele do not havesickle cell disease, and they are resistant to malaria. People whohave…
Chapter 1 Solutions
Genetics: Analysis and Principles
Ch. 1.1 - 1. Which of the following is not a constituent of...Ch. 1.1 - 2. A gene is a segment of DNA that has the...Ch. 1.1 - The function of the genetic code is to a. promote...Ch. 1.1 - The process of transcription directly results in...Ch. 1.2 - Gene expression can be viewed at which of the...Ch. 1.2 - 2. Variation in the traits of organisms may be...Ch. 1.2 - 3. A human skin cell has 46 chromosomes. A human...Ch. 1.2 - 4. Evolutionary change caused by natural selection...Ch. 1.3 - Which of the following is not a model organism? a....Ch. 1.3 - A person studying the rate of transcription of a...
Ch. 1.4 - The scientific method involves which of the...Ch. 1 - Pick any example of a genetic technology and...Ch. 1 - Prob. 2CONQCh. 1 - Most genes encode proteins. Explain how the...Ch. 1 - Prob. 4CONQCh. 1 - Prob. 5CONQCh. 1 - Prob. 6CONQCh. 1 - Prob. 7CONQCh. 1 - Your textbook describes how the detrimental...Ch. 1 - Prob. 9CONQCh. 1 - Prob. 10CONQCh. 1 - Prob. 11CONQCh. 1 - Prob. 12CONQCh. 1 - 13. With regard to biological evolution, which of...Ch. 1 - 14. What are the primary interests of researchers...Ch. 1 - What is a genetic cross?Ch. 1 - Prob. 2EQCh. 1 - Prob. 3EQCh. 1 - 4. Many organisms are studied by geneticists. Do...Ch. 1 - Prob. 5EQ
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