BIOLOGY: CONCEPTS & INVESTIGATIONS LL>C
4th Edition
ISBN: 9781264013548
Author: Hoefnagels
Publisher: MCG CUSTOM
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Chapter 10, Problem 13WIO
Summary Introduction
To explain:
The disorder mode’s of inheritance (autosomal dominant, autosomal recessive or X linked recessive) in a pedigree which is given in the question.
Concept introduction:
Pedigree represents the biological relationship between an individual to its family or ancestors by using the standard symbols. The pedigree is important to predict the dominant or recessive inheritance pattern of the traits and the genetic disorders.
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In the following pedigree, is the disorder’s mode of inheritanceautosomal dominant, autosomal recessive, or X-linked recessive?Explain your reasoning.
What is the most likely pattern of inheritance for this disorder? (Is it autosomal dominant? Autosomal recessive? X-linked dominant? X-linked recessive? Y-linked? Mitochondrial?) Please include two specific pieces of evidence, present within the pedigree, that indicate that this pattern is most likely, as opposed to any other potential pattern. You may assume that the gene responsible for the trait is fully penetrant.
a. The pedigree follows the inheritance of a relatively common trait. Is the trait most likely autosomal dominant, autosomal recessive, X-linked dominant, or X-linked recessive? Explain your reasoning.
b. If the couple marked with a “*” had another child, what is the probability that it would be an affected daughter? (Note: this is a compound outcome.)
Chapter 10 Solutions
BIOLOGY: CONCEPTS & INVESTIGATIONS LL>C
Ch. 10.1 - Describe the relationships among chromosomes, DNA,...Ch. 10.1 - Prob. 2MCCh. 10.2 - Why did Gregor Mendel choose pea plants as his...Ch. 10.2 - Distinguish between dominant and recessive;...Ch. 10.2 - Prob. 3MCCh. 10.3 - What is a monohybrid cross, and what are the...Ch. 10.3 - How are Punnett squares helpful in following...Ch. 10.3 - Prob. 3MCCh. 10.3 - How does the law of segregation reflect the events...Ch. 10.4 - Prob. 1MC
Ch. 10.4 - Prob. 2MCCh. 10.4 - How can the product rule be used to predict the...Ch. 10.5 - How do patterns of inheritance differ for unlinked...Ch. 10.5 - What is the difference between recombinant and...Ch. 10.5 - Prob. 3MCCh. 10.6 - Prob. 1MCCh. 10.6 - Differentiate between pleiotropy and epistasis.Ch. 10.6 - How can the same phenotype stem from many...Ch. 10.6 - Figures 10.18 and 10.20 show two ways that a...Ch. 10.7 - Prob. 1MCCh. 10.7 - Prob. 2MCCh. 10.7 - Why do males and females express recessive...Ch. 10.7 - Prob. 4MCCh. 10.8 - How are pedigrees helpful in determining a...Ch. 10.8 - Prob. 2MCCh. 10.9 - Prob. 1MCCh. 10.9 - What is polygenic inheritance, and how is it...Ch. 10.10 - Prob. 1MCCh. 10.10 - Prob. 2MCCh. 10 - In the list of four terms below, which term is the...Ch. 10 - According to Mendel, if an individual is...Ch. 10 - Prob. 3MCQCh. 10 - Each letter below represents an allele. Which of...Ch. 10 - Which of the following is a possible gamete for an...Ch. 10 - Use the product rule to determine the chance of...Ch. 10 - Refer to the linkage map in figure 10.16b. A...Ch. 10 - How can epistasis decrease the number of...Ch. 10 - Prob. 9MCQCh. 10 - Prob. 10MCQCh. 10 - Prob. 1WIOCh. 10 - Prob. 2WIOCh. 10 - Some people compare a homologous pair of...Ch. 10 - How did Mendel use evidence from monohybrid and...Ch. 10 - Prob. 5WIOCh. 10 - Prob. 6WIOCh. 10 - Prob. 7WIOCh. 10 - Prob. 8WIOCh. 10 - Prob. 9WIOCh. 10 - A family has an X-linked dominant form of...Ch. 10 - X inactivation explains the large color patches in...Ch. 10 - Prob. 12WIOCh. 10 - Prob. 13WIOCh. 10 - Prob. 14WIOCh. 10 - Design an experiment using twins to determine the...Ch. 10 - Prob. 1GPCh. 10 - In Mexican hairless dogs, a dominant allele...Ch. 10 - A species of ornamental fish comes in two colors;...Ch. 10 - Two lizards have green skin and large dewlaps...Ch. 10 - Prob. 5GPCh. 10 - Prob. 6GPCh. 10 - Prob. 7GPCh. 10 - Prob. 8GPCh. 10 - Prob. 1PITCh. 10 - Explain the effects of a mutation, using allele,...Ch. 10 - 3. Add meiosis, gametes, incomplete dominance,...
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- An allele responsible for Marfan syndrome Section 13.4 is inherited in an autosomal dominant pattern. What is the chance that a child will inherit the allele if one parent does not carry it and the other is heterozygous?arrow_forwardThe following pedigree shows the pattern of inheritance of red-green color blindness in a family. Females are shown as circles and males as squares; the squares or circles of individuals affected by the trait are filled in black. What is the chance that a son of the third-generation female indicated by the arrow will be color blind if the father is not color blind? If he is color blind?arrow_forwardAnalysis of X-Linked Dominant and Recessive Traits As a genetic counselor investigating a genetic disorder in a family, you are able to collect a four-generation pedigree that details the inheritance of the disorder in question. Analyze the information in the pedigree to determine whether the trait is inherited as: a. autosomal dominant b. autosomal recessive c. X-linked dominant d. X-linked recessive e. Y-linkedarrow_forward
- Could an individual with blood type O (genotype ii) be a legitimate child of parents in which one parent had blood type A and the other parent had blood type B?arrow_forwardA pedigree analysis was performed on the family of a man with schizophrenia. Based on the known concordance statistics, would his MZ twin be at high risk for the disease? Would the twins risk decrease if he were raised in an environment different from that of his schizophrenic brother?arrow_forwardYou have a true-breeding strain of miniature-winged fruit flies, where this wing trait is recessive to the normal long wings. How would you show whether the miniature wing trait is sex-linked or autosomal?arrow_forward
- Familial retinoblastoma, a rare autosomal dominant defect, arose in a large family that had no prior history of the disease. Consider the following pedigree (the darkly colored symbols represent affected individuals): a. Circle the individual(s) in which the mutation most likely occurred. b. Is the person who is the source of the mutation affected by retinoblastoma? Justify your answer. c. Assuming that the mutant allele is fully penetrant, what is the chance that an affected individual will have an affected child?arrow_forwardPhenylketonuria and alkaptonuria are both autosomal recessive diseases. If a person with PKU marries a person with AKU, what will the phenotype of their children be?arrow_forwardIs this pedigree dominant or recessive. Which best defines this pedigree Autosomal or sex-linked?arrow_forward
- When examining a human pedigree, what features do you look forto distinguish between X-linked recessive inheritance and autosomal recessive inheritance? How would you distinguish X-linkeddominant inheritance from autosomal dominant inheritance in ahuman pedigree?arrow_forwardCould the pedigree in Figure 2-31 be explained as an autosomal dominant disorder? Explain.arrow_forwardThe following pedigree shows what type of inheritance?arrow_forward
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