BIOLOGY
12th Edition
ISBN: 9781260169614
Author: Raven
Publisher: RENT MCG
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Chapter 10, Problem 3A
Genetically, proto-oncogenes act in a dominant fashion. This is because
a. there is only one copy of each proto-oncogene in the genome.
b. they act in a gain-of-function fashion to turn on the cell cycle.
c. they act in a loss-of-function fashion to turn off the cell cycle.
d. they require that both genomic copies are altered to affect function.
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Which of the following demonstrates the link between oncogenes and cancer?
a.Oncogenes do not have mutations that increase the activity or number of molecules that stimulate mitosis.
b.Oncogenes produce molecules that inhibit mitosis.
c.They are genes that transform tumor cells into normal cells.
d.The mutations in oncogenes increase the activity or number of molecules that stimulate mitosis, leading to irregular cell division.
Which of the following best describes a gene that codes for a tumor-suppressor protein?
a. One that helps to prevent progression through the cell cycle.
b. One that helps prevent apoptosis.
c. One that codes for a DNA repair enzyme.
d. One that supports part of a growth factor signaling pathway.
Which of the following statements correctly describes a characteristic of tumor-suppressor gene?
a) they are frequently overexpressed in cancerous cells.
b) they are cancer-causing genes introduced into cells by viruses.
c) they encode proteins that help prevent uncontrolled cell growth.
d) they often encode proteins that stimulate the cell cycle.
Chapter 10 Solutions
BIOLOGY
Ch. 10.1 - Prob. 1LOCh. 10.2 - Prob. 1LOCh. 10.2 - Distinguish between homologues and sister...Ch. 10.2 - Prob. 3LOCh. 10.3 - Describe the eukaryotic cell cycle.Ch. 10.4 - Prob. 1LOCh. 10.4 - Prob. 2LOCh. 10.5 - Describe the phases of mitosis.Ch. 10.5 - Explain the importance of metaphase.Ch. 10.5 - Compare cytokinesis in plants and animals.
Ch. 10.6 - Prob. 1LOCh. 10.6 - Prob. 2LOCh. 10.7 - Prob. 1LOCh. 10.7 - Prob. 2LOCh. 10 - Binary fission in prokaryotes does not require the...Ch. 10 - Chromatin is composed of a. RNA and protein. b....Ch. 10 - What is a nucleosome? a. A region in the cells...Ch. 10 - What is the role of cohesin proteins in cell...Ch. 10 - The kinetochore is a structure that functions to...Ch. 10 - Separation of the sister chromatids occurs during...Ch. 10 - Why is cytokinesis an important part of cell...Ch. 10 - What steps in the cell cycle represent...Ch. 10 - Cyclin-dependent kinases (Cdks) are regulated by...Ch. 10 - Prob. 2ACh. 10 - Genetically, proto-oncogenes act in a dominant...Ch. 10 - The metaphase to anaphase transition involves a....Ch. 10 - The main difference between bacterial cell...Ch. 10 - In animal cells, cytokinesis is accomplished by a...Ch. 10 - Regulation of the cell cycle is very complex and...Ch. 10 - Review you knowledge of signaling pathways...Ch. 10 - Compare and contrast how mutations in cellular...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- The term differentiation refers to (a) the loss of genes from cells. (b) the acquisition of new functional capabilities by cells. (c) the production of functionally specialized cells. (d) the division of genes among different types of cells.arrow_forwardWhich of the following mutations is MOST likely to cause cancer? A) a mutation that causes a cyclin gene to be expressed at all times during the cell cycle B) a mutation that causes an oncogene to be turned off so that no protein is made C) a mutation that causes a Cdk gene to be turned off so that no protein is made D) a mutation that causes a tumor suppressor gene to be over-expressedarrow_forwardStargardt's disease was one of these that can be treated using embryonic stem cells. Why would scientist chose to use this type of stem cell in treatment of Stargard's? A. There ae not ethical issue concerning their use B. They retain stem cell properties even after specialization C. They are able to differentiate into the required cell type D. They are already specialized for this funtionarrow_forward
- A. Which genes could be used to monitor the process of the disease? B.  If you worked for a drug company developing a treatment for the cancer, which genes would you target to turn on in cancer cells? C. Which genes would you target to turn off in cancer cells?arrow_forwardMuscle cells differ from nerve cells mainly because they(A) express different genes.(B) contain different genes.(C) use different genetic codes.(D) have unique ribosomes.arrow_forwardWhich of the following describes an oncogene Group of answer choices A. a gene that stimulates cell division that is malfunctioning B. a cell whose normal function is to cause cancer C. a gene that controls body axes D. a hox gene E. a gene that prevents tumorsarrow_forward
- In a wild-type cell, the function of a protein encoded by a tumor-suppressor gene is to cause a cell to ______. A.) stop dividing B.)extend its telomeres C.) grow toward a new blood vessel D.) respond to a growth factorarrow_forwardWhy is it easier to manipulate embryonic stem cells to differentiate into various tissues than it is to manipulate a typical adult cell? a. As cells develop, signaling pathways can cause some genes to be turned off during development. b. Adult cells have different DNA content than do embryonic stem cells. c. Emybronic stem cells pose less of a threat for organ rejection as do an individual s own adult cells. d. It is no easier to manipulate emybronic stem cells to differentiate into various tissues than it is to manipulate a typical adult cell.arrow_forward________ are changes to the nucleotides in a segment of DNA that codes for a protein. a. Proto-oncogenes b. Tumor suppressor genes c. Gene mutations d. Negative regulatorsarrow_forward
- Most forms of cancer involvea. the activation of a single oncogene.b. the inactivation of a single tumor-suppressor gene.c. the activation of multiple oncogenes.d. the activation of multiple oncogenes and the inactivation ofmultiple tumor-suppressor genes.arrow_forwardImagine you have used cBioportal and breast cancer patient datasets and identified a cancer-associated mutation in a particular protein. What would you do next to understand whether that mutation contributes to tumor progression (include experimental approach)?arrow_forwardWhich of the following accurately compares tumor suppressor genes and proto-oncogenes? A. Both tumor suppressor and proto-oncogenes prevent the spread of cancer by targeting and destroying existing cancer cells. B. A person who has both tumor suppressor and proto-oncogenes will always develop cancer. C. Proto-oncogenes code for growth factors, while tumor suppressor genes inhibit cell division of damaged cells. D. When a proto-oncogene mutates, it becomes a tumor suppressor gene.arrow_forward
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