Biology
11th Edition
ISBN: 9781259188138
Author: Peter H Raven, George B Johnson Professor, Kenneth A. Mason Dr. Ph.D., Jonathan Losos Dr., Susan Singer
Publisher: McGraw-Hill Education
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Chapter 10, Problem 3S
Compare and contrast how mutations in cellular proto-oncogenes and in tumor-suppressor genes can lead to cancer cells.
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Compare and contrast oncogenes and tumor suppressor genes.
Compare and contrast the genetic defects that can lead to disruption of a tumor suppressor gene compared to the mechanisms for activation of oncogenes.
Describe, using specific examples, the differences in how a growth factor gene and a tumor suppressor gene can become oncogenes.
Chapter 10 Solutions
Biology
Ch. 10 - Binary fission in prokaryotes does not require the...Ch. 10 - Chromatin is composed of a. RNA and protein. b....Ch. 10 - What is a nucleosome? a. A region in the cells...Ch. 10 - What is the role of cohesin proteins in cell...Ch. 10 - The kinetochore is a structure that functions to...Ch. 10 - Separation of the sister chromatids occurs during...Ch. 10 - Why is cytokinesis an important part of cell...Ch. 10 - What steps in the cell cycle represent...Ch. 10 - Cyclin-dependent kinases (Cdks) are regulated by...Ch. 10 - Prob. 2A
Ch. 10 - Genetically, proto-oncogenes act in a dominant...Ch. 10 - The metaphase to anaphase transition involves a....Ch. 10 - The main difference between bacterial cell...Ch. 10 - In animal cells, cytokinesis is accomplished by a...Ch. 10 - Regulation of the cell cycle is very complex and...Ch. 10 - Review you knowledge of signaling pathways...Ch. 10 - Compare and contrast how mutations in cellular...
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- Another model, the random model, proposes that any cell in a malignant tumor has the potential to form a new tumor. Does the cancer stem cell hypothesis contradict this idea?arrow_forward________ are changes to the nucleotides in a segment of DNA that codes for a protein. a. Proto-oncogenes b. Tumor suppressor genes c. Gene mutations d. Negative regulatorsarrow_forwardare changes to the order of nucleotides in a segment of DNA that codes for a protein. Proto-oncogenes Tumor suppressor genes Gene mutations Negative regulatorsarrow_forward
- A gene that codes for a positive cell cycle regulator is called a(n) _______. a. kinase inhibitor b. tumor suppressor gene c. proto-oncogene d. oncogenearrow_forwardExplain the difference between a proto-oncogene and a tumor-suppressor gene.arrow_forwardcompare and contrast cancer caused by viruses and cancer caused by oncogenesarrow_forward
- Compare and contrast oncogenes and supressor genes. Give an example of a gene of each kind and a cancer type associated with mutations in said gene.arrow_forwardCompare and contrast oncogenes versus tumor-suppressorgenes.arrow_forwardDescribe the roles of proto-oncogenes and tumor suppressor genes in controlling cell growth, and discuss how some viruses can circumvent this control.arrow_forward
- Explain how mutations in oncogenes and in tumor suppressorgenes cause cancer.arrow_forwardIn some cancer cells, a specific gene has been duplicated many times. Is this gene likely to be an oncogene or a tumor-suppressor gene? Explain your reasoningarrow_forwardDefine tumor-suppressor genes. Why is a mutation in a single copy of a tumor-suppressor gene expected to behave as a recessive gene?arrow_forward
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