Fundamentals of Biostatistics
Fundamentals of Biostatistics
8th Edition
ISBN: 9781305268920
Author: Bernard Rosner
Publisher: Cengage Learning
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Ankylosing spondylitis is an inflammatory disease which affects the spine and sacroiliac joint and can lead to the fusing of vertebrae in the spine. Exercise is important in helping manage pain, therefore a pharmaceutical company wanted to test if their new biologic would increase the time a patient could exercise before experiencing discomfort. The following table gives the time (in minutes) seven patients were able to exercise before reporting pain, both at baseline and then again after six months of taking the biologic.Exercise Time (in minutes)Subject 1 Baseline 30 Post-treatment 40Subject 245 40Subject 350 60Subject 435 37Subject 555 60Subject 620 25Subject 775 75Assume the population(s) of all exercise times is (are) normally distributed. Use JMP to test whether the evidence suggests that the time a person with ankylosing spondylitis can exercise before experiencing discomfort increases after taking this new biologic. Validate the test statistic from JMP by computing it manually.…
Traumatic Brain Injury (TBI) is a significant health problem. TBI is caused by impacts to the head that might occurduring contact sports, motor vehicle accidents, and similar events. TBI is known to produce cognitive impairments and reductions in brain volume. In a recent, repeated-measures study on TBI, Zagorchev et al.(2016) observed that the size of the amygdala among mild TBI patients was reduced at 12 months after injury, relative to two months after injury. Suppose that a researcher is interested in replicating and extending this observation. She recruits n=8 participants with mild TBI and records the volume of a brain region at 2 months and again and again at 12 months. Her data are listed below a.) Test the hypothesis that volume of the brain region changed between 2 & 12 months. Use α=0.05, two-tailed b.) Compute the 80% confidence interval for the mean change in attention span for the population
Which graph used in a residual analysis provides roughly the same information as a scatterplot? What advantages does it have over a scatterplot?
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