Campbell Essential Biology (7th Edition)
Campbell Essential Biology (7th Edition)
7th Edition
ISBN: 9780134765037
Author: Eric J. Simon, Jean L. Dickey, Jane B. Reece
Publisher: PEARSON
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Chapter 10, Problem 8SQ
Summary Introduction

Introduction:

“Mutation” is a phenomenon which causes a change in the nucleotide base in a given nucleotide sequence. It changes the nucleotide present on the DNA sequence. It occurs due to the effect of the radiations like ultra-violet radiations, infra-red radiations and insertion of the foreign DNA inside the cell. This occurs during the process of recombination of the chromosomes.

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A genetic researcher notices that individuals with a particular genetic disease have a shortened version of key protein involved in the diseased biochemical pathway. Which of the following mutations is most likely to result in the premature termination of protein synthesis? A. The disease is caused by a silent mutation. B. The disease is caused by a frameshift mutation. C. The disease is caused by a missense mutation. D. The disease is caused by a nonsense mutation.
Which type of point mutation does not affect the resulting protein? a deletion b missense mutation c silent mutation d nonsense mutation
Finally, imagine that a mutation occurred in the codon below and an A was inserted between the two Ts. How would this affect the mRNA and the amino acid for that codon? Old DNA codon Old RNA codon Old amino acid New DNA codon New mRNA codon New amino acid T  T  G     T  A T  G       This would be an example of which type of a mutation?__________________________
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