ESSENTIALS OF GENETICS ALC & MOD MSTG/ET VP
ESSENTIALS OF GENETICS ALC & MOD MSTG/ET VP
1st Edition
ISBN: 9780134452890
Author: KLUG
Publisher: Pearson Education
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Chapter 11, Problem 16PDQ
Summary Introduction

To review:

The viral DNA having the length of 50 μm and the diameter of 20 Å, and whether the genome will fit into the viral head of 0.08 Å diameter or not.

Introduction:

The virus is described as the entities that perform all the biological activities inside the host cell. The genome of the virus is tightly packed inside the small head of the virus. This is achieved by the packaging of the genome in the condensed form. Different proteins are involved in the packaging of the genome in the head of the virus.

Length of viral DNA=50 µm, Diameter of circular DNA=20 Å,Diameter of viral head=0.08 µm

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A biological motor used to package double-stranded (ds) DNA into viral capsids is able toexert 50 pN of force. A. If the active site has a surface area of 10^-17 m2 , to what pressure can the biological motor package dsDNA within the viral capsid before stalling? B.If the viral capsid has a radius of 30 nm, how much potential energy is stored due to the pressure-confinement of the dsDNA within the capsid? C. Compare this to thermal energy at room temperature, kBT, where kB=1.38*10^-23 J/K is the Boltzmann constant.
The base composition of an RNA virus was analyzed and found to be 14.1% A, 14.0% U, 36.2% G, and 35.7% C. Would you conclude that the viral genetic material is single-stranded RNA or doublestranded RNA?
RNA was extracted from certain virus and found to contain 35% cytosine. With this information, is it possible to predict what percentage of the bases in virus are adenine? If so, what percentage? If not, why not?
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What Is A Virus ? ; Author: Peekaboo Kidz;https://www.youtube.com/watch?v=YS7vsBgWszI;License: Standard YouTube License, CC-BY